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Helical l-Leu-Based Peptides Having Chiral Five-Membered Carbocyclic Ring Amino Acids with an Ethylene Acetal Moiety
http://hdl.handle.net/10069/38332
http://hdl.handle.net/10069/3833288253ea2-1903-4a32-b6d7-3f5fadef4c34
名前 / ファイル | ライセンス | アクション |
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ChemSelect2_8108.pdf (894.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-09-11 | |||||
タイトル | ||||||
タイトル | Helical l-Leu-Based Peptides Having Chiral Five-Membered Carbocyclic Ring Amino Acids with an Ethylene Acetal Moiety | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | amino acids | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | conformation analysis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | helical structures | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | peptides | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Koba, Yurie
× Koba, Yurie× Ueda, Atsushi× Oba, Makoto× Doi, Mitsunobu× Demizu, Yosuke× Kurihara, Masaaki× Tanaka, Masakazu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | l?Leu-based heteropeptides having (R)- or (S)-chiral five-membered carbocyclic ring amino acids (Ac5c3EG) with an ethylene acetal moiety were prepared. A conformational analysis using FT-IR absorption, 1H NMR, and circular dichroism (CD) spectra revealed that l?Leu-based hexapeptides and nonapeptides having (R)- or (S)-Ac5c3EG formed right-handed (P) helical structures in solution. An X-ray crystallographic analysis of nonapeptides 5 a and 5 b showed similar right-handed (P) α-helical structures, without an intramolecular hydrogen bond of the peptide N?H????O? (acetal) type. | |||||
書誌情報 |
ChemistrySelect 巻 2, 号 26, p. 8108-8114, 発行日 2017-09-11 |
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出版者 | ||||||
出版者 | Wiley-VCH Verlag GmbH & Co. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 23656549 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1002/slct.201700832 | |||||
権利 | ||||||
権利情報 | c 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: ChemistrySelect, 2(26), pp.8108-8114; 2017, which has been published in final form at http://dx.doi.org/10.1002/slct.201700832. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | ChemistrySelect, 2(26), pp.8108-8114; 2017 |