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GALT carcinoma: three case reports with glycoprotein 2 immunohistochemistry and electron microscopic observations
http://hdl.handle.net/10069/38612
http://hdl.handle.net/10069/386124920ed1b-8724-4bd0-a89a-5af5f1d70209
名前 / ファイル | ライセンス | アクション |
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Histopathology73_521.pdf (1.5 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-04-24 | |||||
タイトル | ||||||
タイトル | GALT carcinoma: three case reports with glycoprotein 2 immunohistochemistry and electron microscopic observations | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | adenocarcinoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | colon | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | glycoprotein | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gut-associated lymphoid tissue | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | M cell | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Hayashi, Hiroko
× Hayashi, Hiroko× Ohtani, Masashi× Sada, Yuki× Iwasaki, Keisuke× Shimokawa, Isao |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Aims: Gut-associated lymphoid tissue (GALT) carcinoma is a rare colorectal tumour that arises in the epithelium covering GALT. GALT carcinoma is a differentiated tubular adenocarcinoma with dense lymphoid tissue with a characteristically well-demarcated margin. To date, 26 cases of GALT carcinoma, including the three cases discussed here, have been reported. Most (24 of 26) were discovered at early stages and none of the cases have documented any metastases. This suggests that GALT carcinoma may have a favourable prognosis. It is hypothesised that GALT carcinoma originates from M cells in specialised epithelia covering GALT. However, this hypothesis has yet to be confirmed. Methods and results: In this study, we examined three cases of GALT carcinoma by immunohistochemistry detection of glycoprotein 2, a specific marker for M cells, and electron microscopy. Our findings showed that the tumour cells of GALT carcinoma in all three cases were negative for M cells. We thus concluded that GALT carcinoma may be a tubular adenocarcinoma arising by chance in the GALT. This unique carcinoma is a diferentiated adenocarcinoma that grows slowly with the development of GALT. Conclusions: We propose that GALT carcinoma should be classified separately because of its histological setting and good prognosis. | |||||
書誌情報 |
Histopathology 巻 73, 号 3, p. 521-528, 発行日 2018-04-24 |
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出版者 | ||||||
出版者 | John Wiley & Sons Ltd. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03090167 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1111/his.13639 | |||||
権利 | ||||||
権利情報 | c 2018 John Wiley & Sons Ltd. This is the peer reviewed version of the following article: Histopathology, 73(3), pp.521-528; 2018 , which has been published in final form at doi.org/10.1111/his.13639. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Histopathology, 73(3), pp.521-528; 2018 |