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Subclinical inflammation in a case of menstruation-induced familial Mediterranean fever: A case report
http://hdl.handle.net/10069/38677
http://hdl.handle.net/10069/38677ebe42d62-1979-48d9-b028-7de0e1893792
名前 / ファイル | ライセンス | アクション |
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Medicine97_12305.pdf (221.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-11-01 | |||||
タイトル | ||||||
タイトル | Subclinical inflammation in a case of menstruation-induced familial Mediterranean fever: A case report | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Hara, Kazusato
× Hara, Kazusato× Endo, Yushiro× Ishida, Midori× Fujita, Yuya× Tsuji, Sosuke× Takatani, Ayuko× Shimizu, Toshimasa× Sumiyoshi, Remi× Igawa, Takashi× Umeda, Masataka× Fukui, Shoichi× Nishino, Ayako× Kawashiri, Shin-ya× Iwamoto, Naoki× Ichinose, Kunihiro× Tamai, Mami× Nakamura, Hideki× Origuchi, Tomoki× Migita, Kiyoshi× Kawakami, Atsushi× Koga, Tomohiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | PATIENT CONCERNS: A 31-year-old Japanese woman suffered high fever and arthralgia lasting for 2 to 3 days after each menstrual period's start. She was admitted to our hospital, and colchicine was administered immediately after her next period's start, and the febrile attack was completely prevented.DIAGNOSES: We eventually diagnosed typical FMF.INTERVENTIONS: Her remission has been maintained by intermittent colchicine therapy. RATIONALE: Because most patients with familial Mediterranean fever (FMF) have attacks without any prodromal symptoms, and since it is suggested that patients with FMF have subclinical inflammation even during remission, a daily continuous administration of colchicine is recommended for patients with FMF even during remission. However, it is possible that intermittent colchicine therapy only during FMF attacks prevents the attacks completely in patients with FMF with expectable attacks.OUTCOMES: The genetic analysis revealed the G304R heterozygous mutation in exon 2 of the MEFV gene. Cytokine analysis suggested subclinical inflammation during the remission period.LESSONS: This case suggests that taking an extensive medical history (including the relationship between fever attack and menstruation) is important in the diagnosis of female patients with FMF. This case also suggests that a continuous administration of colchicine may have to be considered to regulate subclinical inflammation even in patients with FMF with completely expectable attacks. |
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書誌情報 |
Medicine 巻 97, 号 38, p. e12305, 発行日 2018-09-01 |
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出版者 | ||||||
出版者 | Wolters Kluwer Health, Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00257974 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 15365964 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1097/MD.0000000000012305 | |||||
権利 | ||||||
権利情報 | Copyright c 2018 the Author(s). Published by Wolters Kluwer Health,Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Medicine, 97(38), e12305; 2018 |