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Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.
http://hdl.handle.net/10069/23140
http://hdl.handle.net/10069/23140bb356671-f5ff-4c9a-a730-f17aa3020442
名前 / ファイル | ライセンス | アクション |
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AAC54_1639.pdf (465.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-05-10 | |||||
タイトル | ||||||
タイトル | Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Miyazaki, Taiga
× Miyazaki, Taiga× Yamauchi, Shunsuke× Inamine, Tatsuo× Nagayoshi, Yosuke× Saijo, Tomomi× Izumikawa, Koichi× Seki, Masafumi× Kakeya, Hiroshi× Yamamoto, Yoshihiro× Yanagihara, Katsunori× Miyazaki, Yoshitsugu× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A Candida glabrata calcineurin mutant exhibited increased susceptibility to both azole antifungal and cell wall-damaging agents and was also attenuated in virulence. Although a mutant lacking the downstream transcription factor Crz1 displayed a cell wall-associated phenotype intermediate to that of the calcineurin mutant and was modestly attenuated in virulence, it did not show increased azole susceptibility. These results suggest that calcineurin regulates both Crz1-dependent and -independent pathways depending on the type of stress. | |||||
書誌情報 |
Antimicrobial agents and chemotherapy 巻 54, 号 4, p. 1639-1643, 発行日 2010-04 |
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出版者 | ||||||
出版者 | American Society for Microbiology | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00664804 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 10986596 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00542574 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 20100876 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1128/AAC.01364-09 | |||||
権利 | ||||||
権利情報 | Copyright © 2010, American Society for Microbiology. All Rights Reserved. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Antimicrobial agents and chemotherapy, 54(4), pp.1639-1643; 2010 |