A 44-year-old Japanese man with a 14-year history of limited cutaneous systemic sclerosis (SSc) was admitted with a fever,
hypertension, anemia, thrombocytopenia, and renal dysfunction. On admission, hypertension, hyperreninemia, acute renal dysfunction,hemolytic anemia, and thrombocytopenia led to the diagnosis of scleroderma renal crisis (SRC) complicated with thrombotic microangiopathy (TMA).
The patient had also been infected with influenza B virus almost six days before admission. Following treatment with plasma exchange,an angiotensin-converting enzyme inhibitor, and an anti-virus agent, his general condition improved. He had no risk factors for SRC.In SSc patients, an influenza virus infection might trigger SRC complicated with TMA.
雑誌名
Internal Medicine
巻
58
号
3
ページ
441 - 445
発行年
2019-02-01
出版者
日本内科学会
出版者別言語
The Japanese Society of Internal Medicine
ISSN
09182918
EISSN
13497235
DOI
10.2169/internalmedicine.1441-18
権利
? 2019 The Japanese Society of Internal Medicine. The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Scleroderma Renal Crisis Complicated with Thrombotic Microangiopathy Triggered by Influenza B Virus Infection
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