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Maturation-associated changes in toxicity of the pufferfish Takifugu poecilonotus.
http://hdl.handle.net/10069/22220
http://hdl.handle.net/10069/22220529a91d5-8ff8-49e5-bfa5-432d3eeae727
名前 / ファイル | ライセンス | アクション |
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Toxcon_arakawa_9_9.pdf (171.8 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-10-07 | |||||
タイトル | ||||||
タイトル | Maturation-associated changes in toxicity of the pufferfish Takifugu poecilonotus. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pufferfish | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Takifugu poecilonotus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | tetrodotoxin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | enzyme-linked immunosorbent assay (ELISA) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gonadosomatic index (GSI) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | maturation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ikeda, Koichi
× Ikeda, Koichi× Emoto, Yu× Tatsuno, Ryuhei× Wang, Jun Jie× Ngy, Laymithuna× Taniyama, Shigeto× Takatani, Tomohiro× Arakawa, Osamu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | From October 2006 to December 2007, wild specimens of the pufferfish Takifugu poecilonotus (93 females, 45 males) were collected from the Ariake Sea. Tissue toxicity was examined by mouse bioassay, and tetrodotoxin (TTX) content in the blood plasma by enzyme-linked immunosorbent assay. The relationship between toxicity and maturation was investigated based on changes in the gonadosomatic index: December-March in females and November-March in males, the 'maturation period'; April, 'just after spawning'; and the other months, the 'ordinary period'. Toxicity of both sexes was high throughout the year, but sharply declined in April. In all tissues examined (skin, liver, and ovary) other than testis, toxicity exceeded 1000MU/g or 10,000MU/individual in many individuals. Seasonal profiles of tissue toxicity differed markedly between sexes. In females, liver toxicity was high during the ordinary period, and ovary toxicity was high during the maturation period. In males, little maturation-associated change in the toxin distribution was observed. Plasma TTX levels were similar between the sexes (1.59-15.1MU/ml), and fluctuated largely throughout the year without corresponding changes in tissue toxicity. The percentage of TTX binding to high molecular-weight substances in the plasma varied in association with maturation; the binding ratio fluctuated at relatively low levels during the ordinary period, and stabilized at a high level during the maturation period. | |||||
書誌情報 |
Toxicon 巻 55, 号 2-3, p. 289-297, 発行日 2010-02 |
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出版者 | ||||||
出版者 | Elsevier | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00410101 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00864479 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 19682483 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.toxicon.2009.08.001 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2009 Elsevier Inc. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Toxicon, 55(2-3), pp.289-297; 2010 |