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Evaluation of Glucose Tolerance, Post-Prandial Hyperglycemia and Hyperinsulinemia Influencing the Incidence of Coronary Heart Disease
http://hdl.handle.net/10069/22568
http://hdl.handle.net/10069/2256889a54fbd-d368-42f5-82c3-cb08dea78a31
名前 / ファイル | ライセンス | アクション |
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IM_46_9_543.pdf (453.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-12-04 | |||||
タイトル | ||||||
タイトル | Evaluation of Glucose Tolerance, Post-Prandial Hyperglycemia and Hyperinsulinemia Influencing the Incidence of Coronary Heart Disease | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | coronary heart disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | glucose tolerance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | postprandial glucose | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | postprandial insulin | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yamasa, Toshihiko
× Yamasa, Toshihiko× Ikeda, Satoshi× Koga, Seiji× Kawahara, Eisuke× Muroya, Takahiro× Shinboku, Hiroki× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Recently, the frequency of patients who have glucose intolerance has been increasing in Japan. Glucose intolerance and insulin resistance/hyperinsulinemia are thought to influence the progression of atherosclerosis. The present study examined glucose tolerance, insulin resistance, post-prandial hyperglycemia/hyperinsulinemia and coronary risk factors by using 75 g oral glucose tolerance test (OGTT). Patients and Methods: Coronary risk factors were examined and OGTT with measurement of plasma glucose and serum insulin was done to evaluate the glucose metabolism and insulin resistance in 263 patients who underwent coronary angiography; 202 subjects were diagnosed as having coronary heart disease (CHD) and 61 subjects were normal. We compared the two groups. Results: The rate of having diabetes was significantly high in the CHD group. From the result of OGTT, 22.3% of CHD patients had diabetes mellitus and 36.6% had impaired glucose tolerance, thus the total glucose intolerance rate was 57.7% in the CHD group. No significant difference was noted in the homeostatic model assessment-R (HOMA-R), but glucose and insulin at 2 hours after OGTT were all significantly high in the CHD group. Conclusion: The rate of glucose intolerance and the levels of post-prandial glucose and insulin were high in the CHD group. We concluded that the post-prandial hyperglycemia and hyperinsulinemia influenced the incidence of CHD. | |||||
書誌情報 |
Internal Medicine 巻 46, 号 9, p. 543-546, 発行日 2007-05 |
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出版者 | ||||||
出版者 | 日本内科学会 | |||||
出版者別言語 | ||||||
The Japanese Society of Internal Medicine | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09182918 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2169/internalmedicine.46.6231 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2007 (社)日本内科学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Internal Medicine, vol.46(9), pp.543-546; 2007 |