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Osteoconductivity of hydrothermally synthesized beta-tricalcium phosphate composed of rod-shaped particles under mechanical unloading
http://hdl.handle.net/10069/20913
http://hdl.handle.net/10069/20913737a0212-a58f-4eb0-89fa-240fcd04f8eb
名前 / ファイル | ライセンス | アクション |
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KEM396_253.pdf (3.8 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-02-13 | |||||
タイトル | ||||||
タイトル | Osteoconductivity of hydrothermally synthesized beta-tricalcium phosphate composed of rod-shaped particles under mechanical unloading | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Beta tricalcium phosphate | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bone graft | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Unloading | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Gonda, Yoshinori
× Gonda, Yoshinori× Ioku, Koji× Okuda, Takatoshi× Shibata, Yasuaki× Kamitakahara, Masanobu× Kawachi, Giichiro× Yonezawa, Ikuho× Kurosawa, Hisashi× Ikeda, Tohru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Spherical beta-tricalcium phosphate (β-TCP) granules synthesized using a unique dropping slurry method expressed good osteoconductivity with prominent bone apposition and bioresorbability when implanted into the rat femur (Gonda et al, Key Eng. Mater. 361-363:1013-1016, 2008). The spherical β-TCP granules were implanted into the bone defect created in the distal end of the right femur of each 8-week-old female Wistar rat. To analyze performance of the spherical β-TCP granules as bone substitute in the bone with reduction in osteogenic potential, the right sciatic neurectomy was performed after implantation and the right hind limb was kept unloaded for 2 weeks before euthanization. Four weeks after implantation, some spherical β-TCP granules with resorption in part were surrounded by newly formed bone. Eight and 12 weeks after implantation, most of the residual β-TCP granules were embedded in newly formed bone, and total volume of the implant and newly formed bone was more than the other portions of the bone or the bone of control animals. Osteoclast activity in the implanted area was also higher than the other portions of the bone or the bone of control animals. Replacement of the intraosseous residual β-TCP granules for bone progressed at 12 weeks after implantation compared to those at 8 weeks after implantation. These data suggested that the spherical β-TCP granules stimulated osteogenesis and osteoclast activity of the unloaded bone. | |||||
書誌情報 |
Key Engineering Materials 巻 396-398, p. 253-256, 発行日 2009 |
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出版者 | ||||||
出版者 | Trans Tech Publications Ltd. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 10139826 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10697012 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.4028/0-87849-353-0.253 | |||||
権利 | ||||||
権利情報 | (c) Trans Tech Publications Inc. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関係URI | ||||||
関連名称 | http://www.ttp.net/1013-9826.html | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Key Engineering Materials, 396-398, pp.253-256; 2009 |