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Lack of Efficacy of High-Dose Intravenous Immunoglobulin Treatment of Severe Thrombocytopenia in Patients with Secondary Dengue Virus Infection
http://hdl.handle.net/10069/21868
http://hdl.handle.net/10069/218685b44a287-c1e8-483e-bf05-1a5de4c7cb44
名前 / ファイル | ライセンス | アクション |
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ajtmh77_1135.pdf (108.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-05-13 | |||||
タイトル | ||||||
タイトル | Lack of Efficacy of High-Dose Intravenous Immunoglobulin Treatment of Severe Thrombocytopenia in Patients with Secondary Dengue Virus Infection | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Dimaano, Efren M.
× Dimaano, Efren M.× Saito, Mariko× Honda, Shoko× Miranda, Edna A.× Alonzo, Maria T. G.× Valerio, Myra D.× Mapua, Cynthia A.× Inoue, Shingo× Kumaori, Atsushi× Matias, Ronald× Natividad, Filipinas F.× Oishi, Kazunori |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Because most cases of secondary dengue virus infection are associated with an increased level of platelet-associated IgG, a high dose of intravenous immunoglobulin (IVIG) may have an effect on the development of severe thrombocytopenia in this disease. A randomized, controlled study was conducted with two treatment groups consisting of a treatment (IVIG) group (n = 15) and a non-treatment (non-IVIG) group (n = 16) to determine whether a high dose of IVIG is effective in hastening the recovery from thrombocytopenia in patients with secondary dengue virus infection. No significant difference was found in the baseline demographic data between the two groups. No adverse effect of IVIG was observed, but no effect in hastening the recovery of platelet counts was found in patients with secondary dengue infections. The lack of efficacy of IVIG suggests that platelet clearance by macrophages through Fc {gamma} receptors is not a primary mechanism in this disease. | |||||
書誌情報 |
American Journal of Tropical Medicine and Hygiene 巻 77, 号 6, p. 1135-1138, 発行日 2007-12 |
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出版者 | ||||||
出版者 | American Society of Tropical Medicine and Hygiene | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00029637 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00521439 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 18165536 | |||||
権利 | ||||||
権利情報 | Copyright c 2007 by The American Society of Tropical Medicine and Hygiene | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://www.ajtmh.org/cgi/content/abstract/77/6/1135 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | American Journal of Tropical Medicine and Hygiene, 77(6), pp.1135-1138; 2007 |