WEKO3
アイテム
{"_buckets": {"deposit": "f012f65e-480f-4e6c-b3c5-635d1d2f82b7"}, "_deposit": {"created_by": 2, "id": "17991", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "17991"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00017991", "sets": ["36"]}, "author_link": ["71357", "71355", "71354", "71361", "71360", "71356", "71358", "71359"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "1050", "bibliographicPageStart": "1043", "bibliographicVolumeNumber": "77", "bibliographic_titles": [{"bibliographic_title": "American Journal of Tropical Medicine and Hygiene"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The present study examined the genetic diversity and population structure of Plasmodium falciparum in western Kenya by analyzing the polymorphism of 12 microsatellite loci and two antigen loci. Malaria in highland areas is unstable and epidemic whereas malaria in lowland areas is endemic. Transmission intensity and malaria prevalence are substantially lower in the highlands than in the lowlands. Despite that the highland parasite populations exhibited reduced number of alleles, lower expected heterozygosity, and infection complexity in comparison to the surrounding lowland population, genetic diversity of the highland populations remained high in comparison to parasites from other meso-endemic regions. More than 70% of infections from western Kenya highland study sites were mixed genotype infections. Small but statistically significant genetic differentiation between highland and lowland populations was detected. These findings are discussed in the context of human travel and local transmission in the study area.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "American Journal of Tropical Medicine and Hygiene, 77(6), pp.1043-1050; 2007", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "American Society of Tropical Medicine and Hygiene"}]}, "item_2_relation_11": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "18165519", "subitem_relation_type_select": "PMID"}}]}, "item_2_relation_42": {"attribute_name": "関係URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "http://www.ajtmh.org/cgi/content/abstract/77/6/1043"}]}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright c 2007 by The American Society of Tropical Medicine and Hygiene"}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00521439", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00029637", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Zhong, Daibin"}], "nameIdentifiers": [{"nameIdentifier": "71354", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Afrane, Yaw"}], "nameIdentifiers": [{"nameIdentifier": "71355", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Githeko, Andrew"}], "nameIdentifiers": [{"nameIdentifier": "71356", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yang, Zhaoqing"}], "nameIdentifiers": [{"nameIdentifier": "71357", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Cui, Liwang"}], "nameIdentifiers": [{"nameIdentifier": "71358", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Menge, David M."}], "nameIdentifiers": [{"nameIdentifier": "71359", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Temu, Emmanuel A."}], "nameIdentifiers": [{"nameIdentifier": "71360", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yan, Guiyun"}], "nameIdentifiers": [{"nameIdentifier": "71361", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-23"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ajtmh77_1043.pdf", "filesize": [{"value": "194.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 194900.0, "url": {"label": "ajtmh77_1043.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/17991/files/ajtmh77_1043.pdf"}, "version_id": "3d06e453-8c23-4170-ba8c-2b3803adf236"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Plasmodium falciparum Genetic Diversity in Western Kenya Highlands", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Plasmodium falciparum Genetic Diversity in Western Kenya Highlands"}]}, "item_type_id": "2", "owner": "2", "path": ["36"], "permalink_uri": "http://hdl.handle.net/10069/21869", "pubdate": {"attribute_name": "公開日", "attribute_value": "2009-05-13"}, "publish_date": "2009-05-13", "publish_status": "0", "recid": "17991", "relation": {}, "relation_version_is_last": true, "title": ["Plasmodium falciparum Genetic Diversity in Western Kenya Highlands"], "weko_shared_id": -1}
Plasmodium falciparum Genetic Diversity in Western Kenya Highlands
http://hdl.handle.net/10069/21869
http://hdl.handle.net/10069/21869ce8f37e4-cf00-4c7c-abe9-c17f4db3b3fe
名前 / ファイル | ライセンス | アクション |
---|---|---|
ajtmh77_1043.pdf (194.9 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2009-05-13 | |||||
タイトル | ||||||
タイトル | Plasmodium falciparum Genetic Diversity in Western Kenya Highlands | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Zhong, Daibin
× Zhong, Daibin× Afrane, Yaw× Githeko, Andrew× Yang, Zhaoqing× Cui, Liwang× Menge, David M.× Temu, Emmanuel A.× Yan, Guiyun |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The present study examined the genetic diversity and population structure of Plasmodium falciparum in western Kenya by analyzing the polymorphism of 12 microsatellite loci and two antigen loci. Malaria in highland areas is unstable and epidemic whereas malaria in lowland areas is endemic. Transmission intensity and malaria prevalence are substantially lower in the highlands than in the lowlands. Despite that the highland parasite populations exhibited reduced number of alleles, lower expected heterozygosity, and infection complexity in comparison to the surrounding lowland population, genetic diversity of the highland populations remained high in comparison to parasites from other meso-endemic regions. More than 70% of infections from western Kenya highland study sites were mixed genotype infections. Small but statistically significant genetic differentiation between highland and lowland populations was detected. These findings are discussed in the context of human travel and local transmission in the study area. | |||||
書誌情報 |
American Journal of Tropical Medicine and Hygiene 巻 77, 号 6, p. 1043-1050, 発行日 2007-12 |
|||||
出版者 | ||||||
出版者 | American Society of Tropical Medicine and Hygiene | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00029637 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00521439 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 18165519 | |||||
権利 | ||||||
権利情報 | Copyright c 2007 by The American Society of Tropical Medicine and Hygiene | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://www.ajtmh.org/cgi/content/abstract/77/6/1043 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | American Journal of Tropical Medicine and Hygiene, 77(6), pp.1043-1050; 2007 |