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Biological Differences Between. Polypoid and Nonpolypoid Growth Types of Colorectal Cancer
http://hdl.handle.net/10069/16159
http://hdl.handle.net/10069/1615927c0d1cb-b41c-497f-a84b-a99b263cb4a3
名前 / ファイル | ライセンス | アクション |
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acta45_01_09_t.pdf (800.0 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | Biological Differences Between. Polypoid and Nonpolypoid Growth Types of Colorectal Cancer | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | colorectal cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | polypoid growth | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | PG-type | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | nonpolypoid growth | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | NPG-type | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Nakagoe, Tohru
× Nakagoe, Tohru× Nanashima, Atsushi× Sawai, Terumitsu× Tsuji, Takashi× Ohbatake, Masayuki× Jibiki, Masaaki× Yamaguchi, Hiroyuki× Kurosaki, Nobuko× Yasutaka, Toru× Ayabe, Hiroyoshi× Miyashita, Hiroko× Arisawa, Kokichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background- Two distinct morphologic types of colorectal cancer have been described in recent studies: polypoid growth type (PG-type) and nonpolypoid growth type (NPG-type). Materials and Methods- We investigated possible biological and clinical differences between 37 PG-type and 156 NPGtype cancers using both univariate and multivariate analyses (logistic and Cox regression models). Results- Unlike NPG-type cancers, PG-type cancers had a high proportion of well-differentiated adenocarcinoma cells, a high likelihood of being early colorectal cancers (carcinoma in situ and cancer invades submucosa), and a low frequency of lymph node metastasis. On average, such PG-type cancers also carried a better prognosis than NPG-type cancers (P=0.01). In particular, PG-type cancer patients with stage IV tumors had a better prognosis than NPG-type cancer patients (P=0.02). In fact, after performing a Cox regression analysis, we found that colorectal cancer growth type is an independent prognostic variable, separate from histologic type or stage. Conclusions- PG-type colorectal cancer is less aggressive and has a favorable prognosis compared to NPG-type cancer. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 45, 号 1-2, p. 51-59, 発行日 2000-06-14 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00051-P00059 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 2000, 45(1-2), p.51-59 |