WEKO3
アイテム
{"_buckets": {"deposit": "f6a490f2-14e0-4ef4-a614-f328a754d107"}, "_deposit": {"created_by": 2, "id": "2028", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "2028"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00002028", "sets": ["11"]}, "author_link": ["9325", "9320", "9318", "9315", "9319", "9317", "9326", "9321", "9324", "9322", "9323", "9316"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-06-18", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "101485", "bibliographicVolumeNumber": "39", "bibliographic_titles": [{"bibliographic_title": "Stem Cell Research"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We established three iPSC lines from postmortem-cultured fibroblasts derived following the sudden unexpected death of an 8-year-old girl with Lennox-Gastaut syndrome,\n who turned out to have the R551H-mutant STXBP1 gene. These iPSC clones showed pluripotent characteristics while retaining the genotype and demonstrated trilineage differentiation capability, indicating their utility in disease-modeling studies, i.e., STXBP1-encephalopathy. This is the first report on the establishment of iPSCs from a sudden death child, suggesting the possible use of postmortem-iPSC technologies as an epoch-making approach for precise identification of the cause of sudden death.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Stem Cell Research, 39, art.no.101485; 2019", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier B.V."}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.scr.2019.101485", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2019 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/)."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "18735061", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamamoto, Takuma"}], "nameIdentifiers": [{"nameIdentifier": "9315", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Otsu, Makoto"}], "nameIdentifiers": [{"nameIdentifier": "9316", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okumura, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "9317", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Horie, Yumi"}], "nameIdentifiers": [{"nameIdentifier": "9318", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ueno, Yasuharu"}], "nameIdentifiers": [{"nameIdentifier": "9319", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Taniguchi, Hideki"}], "nameIdentifiers": [{"nameIdentifier": "9320", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohtaka, Manami"}], "nameIdentifiers": [{"nameIdentifier": "9321", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakanishi, Mahito"}], "nameIdentifiers": [{"nameIdentifier": "9322", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Abe, Yuki"}], "nameIdentifiers": [{"nameIdentifier": "9323", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Murase, Takehiko"}], "nameIdentifiers": [{"nameIdentifier": "9324", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umehara, Takahiro"}], "nameIdentifiers": [{"nameIdentifier": "9325", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ikematsu, Kazuya"}], "nameIdentifiers": [{"nameIdentifier": "9326", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-18"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "SCR39_101485.pdf", "filesize": [{"value": "1.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1000000.0, "url": {"label": "SCR39_101485.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/2028/files/SCR39_101485.pdf"}, "version_id": "036e8baa-2ee5-4236-b03a-a7cf9c385ba0"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation"}]}, "item_type_id": "2", "owner": "2", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10069/39324", "pubdate": {"attribute_name": "公開日", "attribute_value": "2019-07-23"}, "publish_date": "2019-07-23", "publish_status": "0", "recid": "2028", "relation": {}, "relation_version_is_last": true, "title": ["Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation"], "weko_shared_id": -1}
Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation
http://hdl.handle.net/10069/39324
http://hdl.handle.net/10069/39324e69bdad8-8983-4157-8669-d1d9a0f2f30b
名前 / ファイル | ライセンス | アクション |
---|---|---|
SCR39_101485.pdf (1.0 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2019-07-23 | |||||
タイトル | ||||||
タイトル | Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yamamoto, Takuma
× Yamamoto, Takuma× Otsu, Makoto× Okumura, Takashi× Horie, Yumi× Ueno, Yasuharu× Taniguchi, Hideki× Ohtaka, Manami× Nakanishi, Mahito× Abe, Yuki× Murase, Takehiko× Umehara, Takahiro× Ikematsu, Kazuya |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We established three iPSC lines from postmortem-cultured fibroblasts derived following the sudden unexpected death of an 8-year-old girl with Lennox-Gastaut syndrome, who turned out to have the R551H-mutant STXBP1 gene. These iPSC clones showed pluripotent characteristics while retaining the genotype and demonstrated trilineage differentiation capability, indicating their utility in disease-modeling studies, i.e., STXBP1-encephalopathy. This is the first report on the establishment of iPSCs from a sudden death child, suggesting the possible use of postmortem-iPSC technologies as an epoch-making approach for precise identification of the cause of sudden death. |
|||||
書誌情報 |
Stem Cell Research 巻 39, p. 101485, 発行日 2019-06-18 |
|||||
出版者 | ||||||
出版者 | Elsevier B.V. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18735061 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.scr.2019.101485 | |||||
権利 | ||||||
権利情報 | c 2019 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Stem Cell Research, 39, art.no.101485; 2019 |