Asymmetric desymmetrization of meso-vic-diols was performed by tosylation in the presence of copper(II) triflate and (R,R)-Ph-BOX as a catalyst. The method was successfully applied to asymmetric desymmetrization of cyclic and acyclic meso-vic-diols in high enantioselectivity with up to >99% ee.
雑誌名
Tetrahedron Letters
巻
48
号
43
ページ
7605 - 7609
発行年
2007-10-22
出版者
Elsevier
ISSN
00404039
書誌レコードID
AA00861801
DOI
10.1016/j.tetlet.2007.08.104
権利
Copyright c 2007 Elsevier Ltd All rights reserved.