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Synthesis and Antimicrobial Activity of Nitrobenzyl-oxy-phenol Derivatives
http://hdl.handle.net/10069/37351
http://hdl.handle.net/10069/373510098768f-847a-4647-a185-257cf599ffce
名前 / ファイル | ライセンス | アクション |
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BPBul39_1888.pdf (347.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-05-23 | |||||
タイトル | ||||||
タイトル | Synthesis and Antimicrobial Activity of Nitrobenzyl-oxy-phenol Derivatives | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Antimicrobial activity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Monobenzone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Moraxella catarrhalis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Phenol | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Mohamed, Malik Suliman
× Mohamed, Malik Suliman× Maki, Toshihide× Shah, Mohammad Monir× Ichinose, Yoshio |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Two hydroquinone derivatives were prepared and their antimicrobial activity evaluated. Their minimum inhibitory concentrations (MICs) were determined using a broth dilution method. Gentamycin and ciprofloxacin were used as reference antibiotics. The antimicrobial activity of 4-(benzyloxy)phenol (monobenzone) was also evaluated based on its structural similarity to the new compounds; activity was comparable to that of 3,5-dimethyl-4-((4-nitrobenzyl)oxy)phenol (4a). 2,3,5-Trimethyl-4-((4-nitrobenzyl)oxy)phenol (4b) exhibited the best antibacterial activity against both clinical isolates and type strain of Moraxella catarrhalis (M. catarrhalis), with a MIC value of 11 μM, comparable to ciprofloxacin 9 μM. | |||||
書誌情報 |
Biological & Pharmaceutical Bulletin 巻 39, 号 11, p. 1888-1892, 発行日 2016-11-01 |
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出版者 | ||||||
出版者 | 日本薬学会 | |||||
出版者別言語 | ||||||
Pharmaceutical Society of Japan | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09186158 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13475215 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/bpb.b16-00608 | |||||
権利 | ||||||
権利情報 | c 2016 The Pharmaceutical Society of Japan | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Biological & Pharmaceutical Bulletin, 39(11), pp.1888-1892; 2016 |