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Preventive effects of elaszym on malondialdehyde-induced arterial lesions in chickens
http://hdl.handle.net/10069/15754
http://hdl.handle.net/10069/1575439db1bf2-fe87-4e55-859f-5f0245e80869
名前 / ファイル | ライセンス | アクション |
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acta34_02_02_t.pdf (1.2 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | Preventive effects of elaszym on malondialdehyde-induced arterial lesions in chickens | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Toda, Takayoshi
× Toda, Takayoshi× Hamada, Yuhshi× Miura, Myota× Sugamata, Masao× Kitsukawa, Keizo× Yamashiro, Tetsu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Thirty-nine hens, 3 weeks of age, were divided into 6 groups with different treatment as follows ; group A with corn oil injection, group B with corn oil injection and cholesterol feeding, group C with injection of a malondialdehyde solution, group D with injection of malondialdehyde solution and administration of elaszym, group E with injection of malondialdehyde solution and cholesterol feeding and group F with injection of malondialdehyde solution, cholesterol feeding and administration of elaszym. Corn oil and 50% malondialdehyde in corn oil were subcutaneously injected at respective doses of 0.5 and 1ml per kg body weight 12 times for 4 weeks. A diet containing 1% cholesterol without supplementary fat was fed adlibitum. Elaszym was orally administered daily at a dose of 1,500 EU per Kg body weight. A slight increase of plasma cholesterol was seen in group B. A small number of degenerate cells were seen in groups A and B. The plasma malondialdehyde levels were markedly increased in groups C and E. The result of malondialdehyde injection was a significant increase in the number of degenerate cells without stainable lipid in the abdominal aorta from group C. The feeding of a cholesterol-containing diet in combination with molon-dialdehyde injection produced numerous degenerate cells with or without stainable lipid in the abdominal aorta from group E. The administration of elaszym decreased the tissue level of malondialdehyde and the frequency of degenerate cells with or without stainable lipid in the abdominal aortas from groups D and F. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 34, 号 2-4, p. 5-11, 発行日 1989-12-09 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00005-P00011 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1989, 34(2-4), p.5-11 |