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Lectin Immunohistochemistry in Human Non-Malignant and Malignant Gallbladder Tissuses
http://hdl.handle.net/10069/15887
http://hdl.handle.net/10069/15887efaff368-4cc7-4314-8fd7-a9e58b8fdd07
名前 / ファイル | ライセンス | アクション |
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acta36_01_32_t.pdf (1.0 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | Lectin Immunohistochemistry in Human Non-Malignant and Malignant Gallbladder Tissuses | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Muazzam, Faisal
× Muazzam, Faisal× Toda, Takayoshi× Tomita, Shuji× Deguchi, Shigeru× Muto, Yoshihiro× Ono, Iwao |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Changes in the lectin binding pattern in non-malignant and malignant gallbladder tissues were examined using the following eight types of carbohydrate binding lectins : Ulex europaeus-1 (UEA-1), Arachis hypogaea (PNA), Griffonia simplicifolia (GS-1), Glycine maximum (SBA), Bauhinia purpurea (BPA), Dolichos biflorus (DBA), Canavalia ensiformis (Con-A), and Triticum vulgare (WGA). We used a total of 109 tissues including 31 normal tissues, 25 metaplasias, and 53 carcinomas. Lectin staining pattern was evaluated using the Hamada's crieria of the following four types : apical type, cytoplasmic type with polarity, cytoplasmic type without polarity, and stromal type. Normal cases showed apical type and cytoplasmic type with polarity, while carcinoma cases revealed cytoplasmic type with or without polarity. In carcinoma cases, GS-I and DBA lectins showed higher immunohistochemical positive rate and more frequent cytoplasmic type with polarity pattern of immunohistochemical localization than the other types of lectins. These results suggest that the GS-I and DBA are the most reliable lectin marker for malignant transformation of the gallbladder tissues. Key words : Lectin, immunohistochemistry, gallbladder carcinoma. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 36, 号 1-4, p. 176-184, 発行日 1991-12-25 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00176-P00184 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1991, 36(1-4), p.176-184 |