WEKO3
アイテム
{"_buckets": {"deposit": "0814976d-bf71-49a7-9ebd-012a9195f3b7"}, "_deposit": {"created_by": 2, "id": "23150", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "23150"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00023150", "sets": ["56"]}, "author_link": ["97703", "97701", "97698", "97702", "97704", "97699", "97700"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "272", "bibliographicPageStart": "269", "bibliographicVolumeNumber": "48", "bibliographic_titles": [{"bibliographic_title": "Journal of Health Science"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We describe a novel approach to evaluating the respiratory toxicity of chemicals in the free-living nematode Caenorhabditis elegans. Using DOX-96KT, a general purpose, multi-channel dissolved oxygen (DO) measuring system, we measured the DO concentration in culture media containing C. elegans exposed to chemicals to assay for respiratory toxicity. The current value, which is an index of the dissolved oxygen concentration in culture media, was measured every 10 sec for 30 min at 24°C. We focused on the respiration levels of the exposed worms between 500 and 1800 sec. This method produces results that are similar to the computer tracking system measuring behavioral toxicity. Since it can do multiple dilution series tests at a given time, it is useful for concentration-activity correlation studies. This novel technique is not only an alternative to the computer tracking system for measuring behavioral toxicity but also a rapid sublethal toxicity test for chemical hazard assessment.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Journal of Health Science v.48(3) p.269-272, 2002", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Pharmaceutical Society of Japan"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1248/jhs.48.269", "subitem_relation_type_select": "DOI"}}]}, "item_2_relation_42": {"attribute_name": "関係URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "http://dx.doi.org/10.1248/jhs.48.269"}]}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11316464", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "13449702", "subitem_source_identifier_type": "ISSN"}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1347-5207", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kohra, Shinya"}], "nameIdentifiers": [{"nameIdentifier": "97698", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tominaga, Nobuaki"}], "nameIdentifiers": [{"nameIdentifier": "97699", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takao, Yuji"}], "nameIdentifiers": [{"nameIdentifier": "97700", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagae, Masaki"}], "nameIdentifiers": [{"nameIdentifier": "97701", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishibashi, Yasuhiro"}], "nameIdentifiers": [{"nameIdentifier": "97702", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ueda, Kazuo"}], "nameIdentifiers": [{"nameIdentifier": "97703", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Arizono, Koji"}], "nameIdentifiers": [{"nameIdentifier": "97704", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "JHS48_269.pdf", "filesize": [{"value": "154.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 154000.0, "url": {"label": "JHS48_269.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/23150/files/JHS48_269.pdf"}, "version_id": "8e4d42c1-8bef-4c9e-8adb-d8779bbe1d58"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Caenorhabditis elegans", "subitem_subject_scheme": "Other"}, {"subitem_subject": "respiratory toxicity", "subitem_subject_scheme": "Other"}, {"subitem_subject": "oxygen electrode", "subitem_subject_scheme": "Other"}, {"subitem_subject": "behavioral toxicity", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "A Rapid Respiratory Toxicity Test Using Caenorhabditis elegans with an Oxygen Electrode System", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "A Rapid Respiratory Toxicity Test Using Caenorhabditis elegans with an Oxygen Electrode System"}]}, "item_type_id": "2", "owner": "2", "path": ["56"], "permalink_uri": "http://hdl.handle.net/10069/8365", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-10-12"}, "publish_date": "2007-10-12", "publish_status": "0", "recid": "23150", "relation": {}, "relation_version_is_last": true, "title": ["A Rapid Respiratory Toxicity Test Using Caenorhabditis elegans with an Oxygen Electrode System"], "weko_shared_id": -1}
A Rapid Respiratory Toxicity Test Using Caenorhabditis elegans with an Oxygen Electrode System
http://hdl.handle.net/10069/8365
http://hdl.handle.net/10069/83653ec37036-e269-4c5f-a60c-0dcb90b23f0d
名前 / ファイル | ライセンス | アクション |
---|---|---|
JHS48_269.pdf (154.0 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2007-10-12 | |||||
タイトル | ||||||
タイトル | A Rapid Respiratory Toxicity Test Using Caenorhabditis elegans with an Oxygen Electrode System | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Caenorhabditis elegans | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | respiratory toxicity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | oxygen electrode | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | behavioral toxicity | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kohra, Shinya
× Kohra, Shinya× Tominaga, Nobuaki× Takao, Yuji× Nagae, Masaki× Ishibashi, Yasuhiro× Ueda, Kazuo× Arizono, Koji |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We describe a novel approach to evaluating the respiratory toxicity of chemicals in the free-living nematode Caenorhabditis elegans. Using DOX-96KT, a general purpose, multi-channel dissolved oxygen (DO) measuring system, we measured the DO concentration in culture media containing C. elegans exposed to chemicals to assay for respiratory toxicity. The current value, which is an index of the dissolved oxygen concentration in culture media, was measured every 10 sec for 30 min at 24°C. We focused on the respiration levels of the exposed worms between 500 and 1800 sec. This method produces results that are similar to the computer tracking system measuring behavioral toxicity. Since it can do multiple dilution series tests at a given time, it is useful for concentration-activity correlation studies. This novel technique is not only an alternative to the computer tracking system for measuring behavioral toxicity but also a rapid sublethal toxicity test for chemical hazard assessment. | |||||
書誌情報 |
Journal of Health Science 巻 48, 号 3, p. 269-272, 発行日 2002-06 |
|||||
出版者 | ||||||
出版者 | Pharmaceutical Society of Japan | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13449702 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1347-5207 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11316464 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/jhs.48.269 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://dx.doi.org/10.1248/jhs.48.269 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Health Science v.48(3) p.269-272, 2002 |