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Ecotoxicological Effect of Polycyclic Musks on Caenorhabditis elegans
http://hdl.handle.net/10069/8369
http://hdl.handle.net/10069/836971ef12d0-1eeb-4a55-a761-9db6a3db772d
名前 / ファイル | ライセンス | アクション |
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JHS52_276.pdf (266.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-10-12 | |||||
タイトル | ||||||
タイトル | Ecotoxicological Effect of Polycyclic Musks on Caenorhabditis elegans | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | polycyclic musk | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Caenorhabditis elegans | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | soil organism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphtha-lene | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 1,3,4,6,7,8-hexahydro-4,6,6,7,8-hexamethylcyclopenta-γ-2-benzopyran | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Mori, Taiki
× Mori, Taiki× Morita, Fumiyo× Inokuchi, Ayako× Takao, Yuji× Kohra, Shinya× Tominaga, Nobuaki× Takemasa, Takehiro× Arizono, Koji |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The polycyclic musks (PCMs), 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphtha-lene (AHTN) and 1,3,4,6,7,8-hexahydro-4,6,6,7,8-hexamethylcyclopenta-γ-2-benzopyran (HHCB), are widely used as fragrance compounds in laundry detergents, soaps and cosmetics. To assess the potential toxicological effects associated with AHTN and HHCB, Caenorhabditis elegans (C. elegans) was used as a model organism for eco-toxicity testing. We examined acute toxicity using 50% lethal concentrations (LC50) after 24 hr PCM exposure and also examined changes in the test endpoints of growth and maturation such as body length, percentage of gravid worms and fecundity. The LC50 for C. elegans was found to be more than 255.2 mg/l for AHTN and 194.6 mg/l for HHCB. In growth tests, the lowest observed effect concentrations (LOEC) in C. elegans for AHTN and HHCB were 12.8 mg/l and 9.8 mg/l, respectively. In maturation tests, LOECs were estimated at 6.4 mg/l for AHTN and 9.8 mg/l for HHCB. In reproduction tests, while maximum LOECs of 19.5 mg/l were observed for HHCB, concentrations of more than 25.5 mg/l were obtained for AHTN. | |||||
書誌情報 |
Journal of Health Science 巻 52, 号 3, p. 276-282, 発行日 2006-06 |
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出版者 | ||||||
出版者 | Pharmaceutical Society of Japan | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13449702 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1347-5207 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11316464 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/jhs.52.276 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://dx.doi.org/10.1248/jhs.52.276 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Health Science v.52(3) p.276-282, 2006 |