Clinical manifestations and treatment on dengue hemorrhagic fever (DHF) were summarized based on 13 years experience of the first author at the Pediatric Department, Nakorn Phanom Provincial Hospital, Thailand. DHF is an acute febrile disease, characterized by hemoconcentration, thrombocytopenia, and coagulopathy. The underlying mechanism of increased vascular permeability, leads to hemoconcentration, hypovolemic shock, metabolic abnormalities, then disseminated intravascular coagulation (DIC), if not properly treated. Direct cause of death in DHF is either circulatory failure or massive hemorrhage. Therefore, DHF case management should be directed to correct determination of the stage and grade of the disease, and prescribe proper recipes, such as intravenous infusion and blood transfusion.
雑誌名
熱帯医学 Tropical medicine
巻
36
号
3
ページ
93 - 101
発行年
1994-12-28
ISSN
03855643
書誌レコードID
AN00199644
出版者
長崎大学熱帯医学研究所
出版者別言語
Institute of Tropical Medicine, Nagasaki University
Clinical Manifestations and Treatment of Dengue Hemorrhagic Fever (DHF) by 13 Years Experience, More Than 10,000 Cases
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