A total of 15,183 children under 10 years old (37% of target population) was immunized with JE vaccine in Gia Luong District, Ha Bac Province, Vietnam, in 1993 to 1994. JE virus transmission was investigated by swine antibody survey and virus isolation from field mosquitoes. By the hemagglutination inhibition (HI) test, 73-90% of swine were antibody positive all year round, with high geometric mean titer (GMT) of 92.67-95.14 in May and June. By suckling mouse brain inoculation, 6 JE virus strains were isolated from Culex tritaeniorhynchus and Cx. vishuni, as well as laboratory reared F1 from field-caught Cx. tritaeniorhynchus. Serodiganosis by IgM-capture ELISA (MAC-ELISA) carried out on 60 of 85 clinical encephalitis cases detected 43 positives (71.66%). All these serologically confirmed JE cases had not been vaccinated. The results supported the vaccine efficacy to prevent overt JE.
雑誌名
熱帯医学 Tropical medicine
巻
37
号
4
ページ
129 - 134
発行年
1996-03-29
ISSN
03855643
書誌レコードID
AN00199644
出版者
長崎大学熱帯医学研究所
出版者別言語
Institute of Tropical Medicine, Nagasaki University
Transmission of Japanese Encephalitis (JE) Virus in Gia Luong District, Ha Bac Province, Vietnam, After Je Vaccination, 1993-1994
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