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Conjunctival Sac Microbiome in Infectious Conjunctivitis
http://hdl.handle.net/10069/00041096
http://hdl.handle.net/10069/00041096a4fe08e8-411c-4412-a4bd-b6822fe058e6
名前 / ファイル | ライセンス | アクション |
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Microorganisms9_2095.pdf (3.1 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-12-10 | |||||
タイトル | ||||||
タイトル | Conjunctival Sac Microbiome in Infectious Conjunctivitis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | conjunctival microbiome | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | infectious conjunctivitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | polymerase chain reaction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 16S ribosomal DNA sequencing | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Mohamed, Yasser Helmy
× Mohamed, Yasser Helmy× Uematsu, Masafumi× Morinaga, Yoshitomo× Nguyen, Hien-Anh Thi× Toizumi, Michiko× Sasaki, Daisuke× Yanagihara, Katsunori× Dang, Duc-Anh× Kitaoka, Takashi× Yoshida, Lay-Myint |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Acute bacterial conjunctival infections are common, and this study identified the conjunctival bacterial community in infectious conjunctivitis cases seen at the outpatient clinic of Khanh Hoa General Hospital in Nha Trang, Vietnam from October 2016 through December 2017. Conjunctival swabs were collected and tested using conventional culture, PCR, and 16S ribosomal RNA sequencing. The study included 47 randomly selected patients. More than 98% of all DNA reads represented five bacterial phyla. Three of these phyla constituted 92% of all sequences (Firmicutes (35%), Actinobacteria (31%), and Proteobacteria (26%)). At the genus level, there were 12 common genera that constituted about 61% of all sequence reads. Seven of those genera were common (Streptococcus (10%), Cutibacterium (10%), Staphylococcus (7%), Nocardioides (7%), Corynebacterium 1 (5%), Anoxybacillus (5%), and Acinetobacter (5%)), which encompassed 49% of all reads. As for diversity analysis, there was no difference on PERMANOVA analysis (unweighted UniFrac) for sex (p = 0.087), chemosis (p = 0.064), and unclassified eyedrops (p = 0.431). There was a significant difference in cases with bilateral conjunctivitis (p = 0.017) and for using antibiotics (p = 0.020). Of the predominant phyla, Firmicutes had the highest abundance in bacterial conjunctivitis in this study. Pseudomonas as a resident commensal microbiota may have an important role in the prevention of infection. | |||||
書誌情報 |
Microorganisms 巻 9, 号 10, p. 2095, 発行日 2021-10-04 |
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出版者 | ||||||
出版者 | MDPI | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2076-2607 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/microorganisms9102095 | |||||
権利 | ||||||
権利情報 | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Microorganisms, 9(10), art. no. 2095; 2021 |