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Association between thyroid-stimulating hormone (TSH) and proteinuria in relation to thyroid cyst in a euthyroid general population
http://hdl.handle.net/10069/00041107
http://hdl.handle.net/10069/00041107ce1b702c-603a-4af4-ac5b-20a3193f19f4
名前 / ファイル | ライセンス | アクション |
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JPA40_15.pdf (712.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-12-20 | |||||
タイトル | ||||||
タイトル | Association between thyroid-stimulating hormone (TSH) and proteinuria in relation to thyroid cyst in a euthyroid general population | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Euthyroid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Proteinuria | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | T3 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | T4 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Thyroid cysts | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | TSH | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Shimizu, Yuji
× Shimizu, Yuji× Nabeshima-Kimura, Yuko× Kawashiri, Shin-Ya× Noguchi, Yuko× Minami, Shigeki× Nagata, Yasuhiro× Maeda, Takahiro× Hayashida, Naomi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: High normal levels of thyroid-stimulating hormone (TSH) have been reported to be associated with chronic kidney disease (CKD) among euthyroid individuals. However, there has been only limited research on the association between TSH and proteinuria, a major risk factor for the progression of renal disease. Methods: A cross-sectional study of 1595 euthyroid individuals was conducted. All participants were within the normal range for free triiodothyronine (T3), free thyroxine (T4), and TSH. Analyses were stratified by thyroid cyst status to test the hypothesis that the absence of thyroid cysts, an indicator of latent thyroid damage, is associated with declining ability to synthesis thyroid hormone. Results: For participants with thyroid cysts, a significant inverse association between TSH and proteinuria was observed (adjusted odds ratio (95% confidence intervals) of log-transformed TSH for proteinuria 0.40 (0.18, 0.89)). In participants without thyroid cysts, a significant positive association between those two factors was observed (2.06 (1.09, 3.90)). Conclusions: Among euthyroid individuals in the general population, being in the normal range of TSH was found to have an ambivalent association with proteinuria. Thyroid cyst status could be an effect modifier for those associations. |
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書誌情報 |
Journal of Physiological Anthropology 巻 40, p. art. no. 15, 発行日 2021-10-09 |
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出版者 | ||||||
出版者 | BioMed Central Ltd | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1880-6805 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/s40101-021-00264-y | |||||
権利 | ||||||
権利情報 | © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Physiological Anthropology, 40, art. no. 15; 2021 |