Singlet-oxygen photosensitizers with a tetrad structure and a single BODIPY chromophore: An evidence for transition state stabilization of intersystem crossing
利用統計を見る
Eleven tetrad Boron dipyrromethene (BODIPY) derivatives were synthesized and examined as singlet-oxygen photosensitizers (PSs). It was clearly shown that a charge shifted state (CSS) with a twisted π-bond makes a considerable contributed to the transition state (TS) stabilization at the minimum energy seam of crossing (MESX) for intersystem crossing (ISC). An EC50 of less than 10 nM was achieved for the G361 human melanoma cell line using one of the investigated PSs, which were only composed of 1st− and 2nd-period elements with compact structures.
雑誌名
Dyes and Pigments
巻
210
ページ
110963
発行年
2022-11-25
出版者
Elsevier Ltd
ISSN
01437208
DOI
10.1016/j.dyepig.2022.110963
権利
ⓒ 2022 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
Singlet-oxygen photosensitizers with a tetrad structure and a single BODIPY chromophore: An evidence for transition state stabilization of intersystem crossing
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