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Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in middle-aged and elderly Japanese men
http://hdl.handle.net/10069/38249
http://hdl.handle.net/10069/38249406395c0-3784-4116-bcfb-c6a208cfd863
名前 / ファイル | ライセンス | アクション |
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Medicine97_9962.pdf (179.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-06-01 | |||||
タイトル | ||||||
タイトル | Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in middle-aged and elderly Japanese men | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | bone turnover markers | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | elderly | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | osteoporosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | quantitative ultrasound | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | men | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Nishimura, Takayuki
× Nishimura, Takayuki× Arima, Kazuhiko× Abe, Yasuyo× Kanagae, Mitsuo× Mizukami, Satoshi× Okabe, Takuhiro× Tomita, Yoshihito× Goto, Hisashi× Horiguchi, Itsuko× Aoyagi, Kiyoshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The aim of the present study was to investigate the age-related patterns and the relationships between serum levels of tartrate-resistant acid phosphatase-5b (TRACP-5b) or bone-specific alkaline phosphatase (BAP), and the heel stiffness index measured by quantitative ultrasound (QUS) in 429 Japanese men, with special emphasis on 2 age groups (40-59 years and 60 years or over). The heel stiffness index (bone mass) was measured by QUS. Serum samples were collected, and TRACP-5b and BAP levels were measured. The stiffness index was significantly decreased with age. Log (TRACP-5b) was significantly increased with age, but Log (BAP) was stable. Generalized linear models showed that higher levels of Log (TRACP-5b) and Log (BAP) were correlated with a lower stiffness index after adjusting for covariates in men aged 60 years or over, but not in men aged 40 to 59 years. In conclusion, higher rates of bone turnover markers were associated with a lower stiffness index only in elderly men. These results may indicate a different mechanism of low bone mass among different age groups of men. | |||||
書誌情報 |
Medicine 巻 97, 号 8, p. e9962, 発行日 2018-02 |
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出版者 | ||||||
出版者 | Lippincott Williams and Wilkins Ltd. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00257974 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1097/MD.0000000000009962 | |||||
権利 | ||||||
権利情報 | c 2018 the Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Medicine (United States), 97(8), e9962; 2018 |