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Re-emergence of dengue virus serotype 3 infections in Gabon in 2016?2017, and evidence for the risk of repeated dengue virus infections
http://hdl.handle.net/10069/39610
http://hdl.handle.net/10069/39610edc9bfc6-4014-4348-8ae5-7602d266293d
名前 / ファイル | ライセンス | アクション |
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IJID91_129.pdf (1.2 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-01-10 | |||||
タイトル | ||||||
タイトル | Re-emergence of dengue virus serotype 3 infections in Gabon in 2016?2017, and evidence for the risk of repeated dengue virus infections | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Africa | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Dengue | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Dengue virus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gabon | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Phylogeny | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Surveillance | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Abe, Haruka
× Abe, Haruka× Ushijima, Yuri× Loembe, Marguerite M.× Bikangui, Rodrigue× Nguema-Ondo, Georgelin× Mpingabo, Patrick I.× Zadeh, Vahid R.× Pemba, Christelle M.× Kurosaki, Yohei× Igasaki, Yui× de, Vries Sophia G.× Grobusch, Martin P.× Agnandji, Selidji T.× Lell, Bertrand× Yasuda, Jiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objectives: Dengue outbreaks, mainly caused by dengue virus serotype 2 (DENV-2), occurred in 2007 and in 2010 in Gabon, Central Africa. However, information on DENV infections has been insufficient since 2010. The aim of this study was to investigate the current DENV infection scenario and the risk of repeated infections in Gabon. Methods: During 2015?2017, serum samples were collected from enrolled febrile participants and were tested for DENV infection using RT-qPCR. DENV-positive samples were analyzed for a history of previous DENV infection(s) using ELISA. The complete DENV genome was sequenced to analyze the phylogeny of Gabonese DENV strains. Results: DENV-3 was exclusively detected, with a high rate of anti-DENV IgG seropositivity among DENV-3-positive participants. DENV-3 showed higher infection rates in adults and the infection was seasonal with peaks in the rainy seasons. Phylogenetic analysis revealed that Gabonese DENV-3 originated from West African strains and has been circulating continuously in Gabon since at least 2010, when the first DENV-3 case was reported. Conclusions: These findings indicate stable DENV-3 circulation and the risk of repeated DENV infections in Gabon, highlighting the need for continuous monitoring to control DENV infections. | |||||
書誌情報 |
International Journal of Infectious Diseases 巻 91, p. 129-136, 発行日 2019-12-07 |
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出版者 | ||||||
出版者 | Elsevier Ltd | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 12019712 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.ijid.2019.12.002 | |||||
権利 | ||||||
権利情報 | c 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | International Journal of Infectious Diseases, 91, pp.129-136; 2020 |