Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma that is associated with human immunodeficiency virus (HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an unusual case of HIV-negative PBL that occurred in the sigmoid colon. This patient had a history of systemic lupus erythematosus and an underlying immunosuppressive state from long term steroid therapy. The lymphoma cells were positive for CD138, kappa light chain restriction and Epstein-Barr virus and negative for CD20/L26, CD3, CD79a, UCHL1 (CD45RO) and cytokeratin (AE1/AE3). The patient died approximately 2 mo after the operation. In the present paper, we review cases of PBL of the colon in HIVnegative patients.
雑誌名
World Journal of Gastroenterology
巻
21
号
24
ページ
7598 - 7603
発行年
2015-06-28
出版者
WJG Press
ISSN
10079327
DOI
10.3748/wjg.v21.i24.7598
権利
c2015 Baishideng Publishing Group Inc. All rights reserved. Articles published by this open-access journal are distributed under the terms of the Creative Commons Attribution-Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license.
著者版フラグ
publisher
引用
World Journal of Gastroenterology, 21(24), pp.7598-7603; 2015
Case of plasmablastic lymphoma of the sigmoid colon and literature review
WJG21_7598.pdf
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