WEKO3
アイテム
{"_buckets": {"deposit": "1b655ecc-181c-467e-8466-5b13c299627b"}, "_deposit": {"created_by": 2, "id": "4993", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "4993"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00004993", "sets": ["11"]}, "author_link": ["20536", "20554", "20560", "20529", "20538", "20545", "20559", "20542", "20553", "20550", "20527", "20549", "20533", "20543", "20552", "20534", "20544", "20535", "20555", "20532", "20531", "20526", "20557", "20556", "20547", "20528", "20551", "20546", "20540", "20530", "20548", "20541", "20539", "20537", "20558"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2015-12-12", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "777", "bibliographicVolumeNumber": "8", "bibliographic_titles": [{"bibliographic_title": "BMC Research Notes"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background: Previous genome-wide association studies have evaluated the impact of common genetic variants and identified several non-HLA risk loci associated with autoimmune liver diseases. More recent genome-wide association studies and replication analyses reported an association between variants of the CARD10 polymorphism rs6000782 and risk of type 1 autoimmune hepatitis (AIH). In this case-control study, we genotyped 326 Japanese AIH patients and 214 control subjects. Results: Genomic DNA from 540 individuals of Japanese origin, including 326 patients with type-1 AIH and 214 healthy controls, was analyzed for two single nucleotide polymorphisms (SNPs) in the CARD10 gene. We selected CARD10 rs6000782 SNPs and genotyped these using PCR-RFLP method and direct sequencing. The Chi square test revealed that the rs6000782 variant alle (c) was not associated with the susceptibility for AIH in a Japanese population [p = 0.376, odds ratio (OR) 1.271, 95 % confidence interval (CI) 0.747-2.161] in an allele model. Our data also showed that CARD10 rs6000782 variants were not associated with AIH or with the clinical parameters of AIH. Conclusions: In this study we examined an association between rs6000782 SNPs in the CARD10 gene and type-1 AIH. Results showed no significant association of rs62000782 with type-1 AIH in a Japanese population. This study demonstrated no association between CARD10 rs6000782 variants and AIH in a Japanese population.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "BMC Research Notes, 8, 777; 2015", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "BioMed Central"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1186/s13104-015-1733-4", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2015 Migita et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated."}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "17560500", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Migita, Kiyoshi"}], "nameIdentifiers": [{"nameIdentifier": "20526", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Jiuchi, Yuka"}], "nameIdentifiers": [{"nameIdentifier": "20527", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Furukawa, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "20528", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamura, Minoru"}], "nameIdentifiers": [{"nameIdentifier": "20529", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Komori, Atsumasa"}], "nameIdentifiers": [{"nameIdentifier": "20530", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yasunami, Michio"}], "nameIdentifiers": [{"nameIdentifier": "20531", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kozuru, Hideko"}], "nameIdentifiers": [{"nameIdentifier": "20532", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Abiru, Seigo"}], "nameIdentifiers": [{"nameIdentifier": "20533", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamasaki, Kazumi"}], "nameIdentifiers": [{"nameIdentifier": "20534", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagaoka, Shinya"}], "nameIdentifiers": [{"nameIdentifier": "20535", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hashimoto, Satoru"}], "nameIdentifiers": [{"nameIdentifier": "20536", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Bekki, Shigemune"}], "nameIdentifiers": [{"nameIdentifier": "20537", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshizawa, Kaname"}], "nameIdentifiers": [{"nameIdentifier": "20538", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimada, Masaaki"}], "nameIdentifiers": [{"nameIdentifier": "20539", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kouno, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "20540", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kamitsukasa, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "20541", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Komatsu, Tatsuji"}], "nameIdentifiers": [{"nameIdentifier": "20542", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hijioka, Taizo"}], "nameIdentifiers": [{"nameIdentifier": "20543", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamuta, Makoto"}], "nameIdentifiers": [{"nameIdentifier": "20544", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Naganuma, Atsushi"}], "nameIdentifiers": [{"nameIdentifier": "20545", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamashita, Haruhiro"}], "nameIdentifiers": [{"nameIdentifier": "20546", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishimura, Hideo"}], "nameIdentifiers": [{"nameIdentifier": "20547", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohta, Hajime"}], "nameIdentifiers": [{"nameIdentifier": "20548", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamura, Yoko"}], "nameIdentifiers": [{"nameIdentifier": "20549", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ario, Keisuke"}], "nameIdentifiers": [{"nameIdentifier": "20550", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oohara, Yukio"}], "nameIdentifiers": [{"nameIdentifier": "20551", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugi, Kazuhiro"}], "nameIdentifiers": [{"nameIdentifier": "20552", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tomizawa, Minoru"}], "nameIdentifiers": [{"nameIdentifier": "20553", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Takeaki"}], "nameIdentifiers": [{"nameIdentifier": "20554", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takahashi, Hironao"}], "nameIdentifiers": [{"nameIdentifier": "20555", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Muro, Toyokichi"}], "nameIdentifiers": [{"nameIdentifier": "20556", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Makita, Fujio"}], "nameIdentifiers": [{"nameIdentifier": "20557", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mita, Eiji"}], "nameIdentifiers": [{"nameIdentifier": "20558", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakai, Hironori"}], "nameIdentifiers": [{"nameIdentifier": "20559", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yatsuhashi, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "20560", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BMCRN8_777.pdf", "filesize": [{"value": "964.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 964100.0, "url": {"label": "BMCRN8_777.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/4993/files/BMCRN8_777.pdf"}, "version_id": "f66bea7f-35d2-41a8-81c9-4dadd5ffbc14"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Autoimmune hepatitis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "CARD10", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Genetic factor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Genome-wide association study", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Lack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Lack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population"}]}, "item_type_id": "2", "owner": "2", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10069/36132", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-01-25"}, "publish_date": "2016-01-25", "publish_status": "0", "recid": "4993", "relation": {}, "relation_version_is_last": true, "title": ["Lack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population"], "weko_shared_id": -1}
Lack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population
http://hdl.handle.net/10069/36132
http://hdl.handle.net/10069/36132d6c0abc2-3697-4e48-8cc1-28e29d11bf26
名前 / ファイル | ライセンス | アクション |
---|---|---|
BMCRN8_777.pdf (964.1 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2016-01-25 | |||||
タイトル | ||||||
タイトル | Lack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Autoimmune hepatitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CARD10 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Genetic factor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Genome-wide association study | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Migita, Kiyoshi
× Migita, Kiyoshi× Jiuchi, Yuka× Furukawa, Hiroshi× Nakamura, Minoru× Komori, Atsumasa× Yasunami, Michio× Kozuru, Hideko× Abiru, Seigo× Yamasaki, Kazumi× Nagaoka, Shinya× Hashimoto, Satoru× Bekki, Shigemune× Yoshizawa, Kaname× Shimada, Masaaki× Kouno, Hiroshi× Kamitsukasa, Hiroshi× Komatsu, Tatsuji× Hijioka, Taizo× Nakamuta, Makoto× Naganuma, Atsushi× Yamashita, Haruhiro× Nishimura, Hideo× Ohta, Hajime× Nakamura, Yoko× Ario, Keisuke× Oohara, Yukio× Sugi, Kazuhiro× Tomizawa, Minoru× Sato, Takeaki× Takahashi, Hironao× Muro, Toyokichi× Makita, Fujio× Mita, Eiji× Sakai, Hironori× Yatsuhashi, Hiroshi |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Previous genome-wide association studies have evaluated the impact of common genetic variants and identified several non-HLA risk loci associated with autoimmune liver diseases. More recent genome-wide association studies and replication analyses reported an association between variants of the CARD10 polymorphism rs6000782 and risk of type 1 autoimmune hepatitis (AIH). In this case-control study, we genotyped 326 Japanese AIH patients and 214 control subjects. Results: Genomic DNA from 540 individuals of Japanese origin, including 326 patients with type-1 AIH and 214 healthy controls, was analyzed for two single nucleotide polymorphisms (SNPs) in the CARD10 gene. We selected CARD10 rs6000782 SNPs and genotyped these using PCR-RFLP method and direct sequencing. The Chi square test revealed that the rs6000782 variant alle (c) was not associated with the susceptibility for AIH in a Japanese population [p = 0.376, odds ratio (OR) 1.271, 95 % confidence interval (CI) 0.747-2.161] in an allele model. Our data also showed that CARD10 rs6000782 variants were not associated with AIH or with the clinical parameters of AIH. Conclusions: In this study we examined an association between rs6000782 SNPs in the CARD10 gene and type-1 AIH. Results showed no significant association of rs62000782 with type-1 AIH in a Japanese population. This study demonstrated no association between CARD10 rs6000782 variants and AIH in a Japanese population. | |||||
書誌情報 |
BMC Research Notes 巻 8, p. 777, 発行日 2015-12-12 |
|||||
出版者 | ||||||
出版者 | BioMed Central | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 17560500 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/s13104-015-1733-4 | |||||
権利 | ||||||
権利情報 | c 2015 Migita et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | BMC Research Notes, 8, 777; 2015 |