WEKO3
アイテム
{"_buckets": {"deposit": "007f6e03-cc4e-41de-aefe-28dcdf66746f"}, "_deposit": {"created_by": 2, "id": "5387", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "5387"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00005387", "sets": ["30"]}, "author_link": ["22835", "22834", "22830", "22832", "22831", "22840", "22833", "22839", "22841", "22829", "22836", "22838", "22837"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2014-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "738", "bibliographicPageStart": "736", "bibliographicVolumeNumber": "46", "bibliographic_titles": [{"bibliographic_title": "Transplantation Proceedings"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background As the survival of human immunodeficiency virus (HIV)-infected individuals has improved due to the widespread use of antiretroviral therapy, the mortality rate due to hepatitis C virus (HCV)-related liver disease has increased in HIV/HCV-coinfected patients. Aim The aims of this study were to establish the appropriate therapeutic strategy for HIV/HCV-coinfected patients by evaluating the liver function, including the hepatic functional reserve and portal hypertension, and to investigate the prognosis of HIV/HCV-coinfected patients in Japan. Patients and Methods In addition to regular liver function tests, the hepatic functional reserve of 41 patients with HIV/HCV coinfection was evaluated using the indocyanine green retention rate and liver galactosyl serum albumin-scintigraphy. The data for 146 patients with HIV/HCV coinfection through blood products were extracted from 4 major HIV centers in Japan. In addition to liver function tests, the platelet counts (PLT) were evaluated as a marker of portal hypertension. Results In spite of the relatively preserved general liver function test results, approximately 40% of the HIV/HCV-coinfected patients had an impaired hepatic functional reserve. In addition, while the albumin and bilirubin levels were normal, the PLT was \u003c150,000/μL in 17 patients. Compared with HCV mono-infected patients with a PLT \u003c150,000/μL, the survival of HIV/HCV-coinfected patients was shorter (HCV, 5 years, 97%; 10 years, 86% and HIV/HCV, 5 years, 87%; 10 years, 73%; P \u003c.05). Conclusion These results must be taken into account to establish an optimal therapeutic strategy, including the appropriate timing of liver transplantation in HIV/HCV-coinfected patients in Japan.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Transplantation Proceedings, 46(3), pp.736-738; 2014", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier USA"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.transproceed.2013.11.126", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2014 by Elsevier Inc. All rights reserved."}, {"subitem_rights": "NOTICE: this is the author’s version of a work that was accepted for publication in Transplantation Proceedings\u003e. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Transplantation Proceedings, 46, 3, (2014)"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00411345", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Eguchi, Susumu"}], "nameIdentifiers": [{"nameIdentifier": "22829", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takatsuki, Mitsuhisa"}], "nameIdentifiers": [{"nameIdentifier": "22830", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Soyama, Akihiko"}], "nameIdentifiers": [{"nameIdentifier": "22831", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hidaka, Masaaki"}], "nameIdentifiers": [{"nameIdentifier": "22832", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakao, Kazuhiko"}], "nameIdentifiers": [{"nameIdentifier": "22833", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shirasaka, Takuma"}], "nameIdentifiers": [{"nameIdentifier": "22834", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Masahiro"}], "nameIdentifiers": [{"nameIdentifier": "22835", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tachikawa, Natsuo"}], "nameIdentifiers": [{"nameIdentifier": "22836", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Gatanaga, Hiroyuki"}], "nameIdentifiers": [{"nameIdentifier": "22837", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kugiyama, Yuki"}], "nameIdentifiers": [{"nameIdentifier": "22838", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yatsuhashi, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "22839", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ichida, Takafumi"}], "nameIdentifiers": [{"nameIdentifier": "22840", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kokudo, Norihiro"}], "nameIdentifiers": [{"nameIdentifier": "22841", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "TraPro46_736.pdf", "filesize": [{"value": "222.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 222700.0, "url": {"label": "TraPro46_736.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/5387/files/TraPro46_736.pdf"}, "version_id": "eb9a1cb8-8f98-49a4-845c-4387618a2e94"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "non-cirrhotic portal hypertension", "subitem_subject_scheme": "Other"}, {"subitem_subject": "highly active antiretroviral therapy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "contaminated blood products", "subitem_subject_scheme": "Other"}, {"subitem_subject": "hemophilia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "liver transplantation", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan"}]}, "item_type_id": "2", "owner": "2", "path": ["30"], "permalink_uri": "http://hdl.handle.net/10069/34457", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-06-12"}, "publish_date": "2014-06-12", "publish_status": "0", "recid": "5387", "relation": {}, "relation_version_is_last": true, "title": ["Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan"], "weko_shared_id": -1}
Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan
http://hdl.handle.net/10069/34457
http://hdl.handle.net/10069/34457cbebccba-17ae-4639-90e5-7a78fa5f618f
名前 / ファイル | ライセンス | アクション |
---|---|---|
TraPro46_736.pdf (222.7 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2014-06-12 | |||||
タイトル | ||||||
タイトル | Analysis of the Hepatic Functional Reserve, Portal Hypertension, and Prognosis of Patients With Human Immunodeficiency Virus/Hepatitis C Virus Coinfection Through Contaminated Blood Products in Japan | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | non-cirrhotic portal hypertension | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | highly active antiretroviral therapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | contaminated blood products | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hemophilia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | liver transplantation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Eguchi, Susumu
× Eguchi, Susumu× Takatsuki, Mitsuhisa× Soyama, Akihiko× Hidaka, Masaaki× Nakao, Kazuhiko× Shirasaka, Takuma× Yamamoto, Masahiro× Tachikawa, Natsuo× Gatanaga, Hiroyuki× Kugiyama, Yuki× Yatsuhashi, Hiroshi× Ichida, Takafumi× Kokudo, Norihiro |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background As the survival of human immunodeficiency virus (HIV)-infected individuals has improved due to the widespread use of antiretroviral therapy, the mortality rate due to hepatitis C virus (HCV)-related liver disease has increased in HIV/HCV-coinfected patients. Aim The aims of this study were to establish the appropriate therapeutic strategy for HIV/HCV-coinfected patients by evaluating the liver function, including the hepatic functional reserve and portal hypertension, and to investigate the prognosis of HIV/HCV-coinfected patients in Japan. Patients and Methods In addition to regular liver function tests, the hepatic functional reserve of 41 patients with HIV/HCV coinfection was evaluated using the indocyanine green retention rate and liver galactosyl serum albumin-scintigraphy. The data for 146 patients with HIV/HCV coinfection through blood products were extracted from 4 major HIV centers in Japan. In addition to liver function tests, the platelet counts (PLT) were evaluated as a marker of portal hypertension. Results In spite of the relatively preserved general liver function test results, approximately 40% of the HIV/HCV-coinfected patients had an impaired hepatic functional reserve. In addition, while the albumin and bilirubin levels were normal, the PLT was <150,000/μL in 17 patients. Compared with HCV mono-infected patients with a PLT <150,000/μL, the survival of HIV/HCV-coinfected patients was shorter (HCV, 5 years, 97%; 10 years, 86% and HIV/HCV, 5 years, 87%; 10 years, 73%; P <.05). Conclusion These results must be taken into account to establish an optimal therapeutic strategy, including the appropriate timing of liver transplantation in HIV/HCV-coinfected patients in Japan. | |||||
書誌情報 |
Transplantation Proceedings 巻 46, 号 3, p. 736-738, 発行日 2014-04 |
|||||
出版者 | ||||||
出版者 | Elsevier USA | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00411345 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.transproceed.2013.11.126 | |||||
権利 | ||||||
権利情報 | c 2014 by Elsevier Inc. All rights reserved. | |||||
権利 | ||||||
権利情報 | NOTICE: this is the author’s version of a work that was accepted for publication in Transplantation Proceedings>. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Transplantation Proceedings, 46, 3, (2014) | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Transplantation Proceedings, 46(3), pp.736-738; 2014 |