Mediterranean fever (MEFV) Variant P369S/R408Q in a Patient with Entero-Behcet's Disease who Successfully Responded to Treatment with Colchicine
利用統計を見る
A 57-year-old Japanese woman who had been diagnosed as having entero-Behcet's disease nine years earlier was admitted with a persistent high-grade fever. An Mediterranean fever (MEFV) gene analysis revealed the compound heterozygous P369S-R408Q variant. She was treated with colchicine, and her symptoms immediately improved. Prednisolone (PSL) was added to treat the punched-out ulcers in the terminal ileum, leading to remission. There has been no relapse since the PSL was discontinued. In Behcet's disease patients with MEFV variants, the use of colchicine should therefore be considered in such patients as well as immunosuppressive therapy.
雑誌名
Internal Medicine
巻
53
号
20
ページ
2381 - 2384
発行年
2014-10-15
出版者
日本内科学会
出版者別言語
Japanese Society of Internal Medicine
ISSN
09182918
EISSN
13497235
DOI
10.2169/internalmedicine.53.2872
権利
c 2014 by The Japanese Society of Internal Medicine
Mediterranean fever (MEFV) Variant P369S/R408Q in a Patient with Entero-Behcet's Disease who Successfully Responded to Treatment with Colchicine
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