WEKO3
アイテム
{"_buckets": {"deposit": "af6a251d-9c62-4e80-8806-d84b8ef7b328"}, "_deposit": {"created_by": 2, "id": "589", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "589"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00000589", "sets": ["36"]}, "author_link": ["3035", "3039", "3031", "3036", "3037", "3040", "3034", "3033", "3038", "3032"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020-02-24", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "104264", "bibliographicVolumeNumber": "81", "bibliographic_titles": [{"bibliographic_title": "Infection, Genetics and Evolution"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Influenza virus B belongs to the family Orthomyxoviridae with segmented negative-sense RNA genomes. Since 1970s, influenza B has diverged intoVictoria and Yamagata, which differs in antigenic and evolutionary characteristics. Yet, molecular-epidemiological information of influenza B from developing nations is limited. In central Vietnam, influenza A subtype-specific circulation pattern and clinical characteristics were previously described. However, molecular evolutionary characteristics of influenza B has not been discussed to date. We utilized the influenza B positives obtained from paediatric ARI surveillance during 2007?2013. Influenza B HA and NA genes were amplified, sequenced, and phylogenetic/molecular evolutionary analysis was performed using Maximum Likelihood and Bayesian MCMC. Phylodynamics analysis was performed with Bayesian Skyline Plot (BSP). Furthermore, we performed selection pressure analysis and estimated N-glycosylation sites. In the current study, overall positive rate for influenza B was 3.0%, and Victoria lineage immediately became predominant in post-A/H1N1pdm09 period. The noticeable shift in Victoria lineage WHO Group occurred. With respect to the evolutionary rate (substitutions/site/year), Victoria lineage HA gene was evolving faster than Yamagata lineage (2.43 × 10?3 vs 2.00 × 10?3). Furthermore, the evolutionary rate of Victoria Group 5 was greater than Group 1. BSP presented the rapid growth in Effective Population Size (EPS) of Victoria lineage occurred soon after the 1st A/H1N1pdm09 case was detected whereas the EPS of Yamagata lineage was stable for both genes. N-glycosylation pattern between lineages and among WHO Groups were slightly different, and HA gene had a total of 6 amino acid substitutions under positive section pressure (4 for Victoria and 2 for Yamagata). The current results highlight the importance of Victoria lineage in post-A/H1N1pdm09 period. Difference in evolutionary characteristics and phylodynamics may indicate lineage and WHO Group-specific evolutionary dynamics. It is necessary to further continue the molecular-epidemiological surveillance in local setting to gain a better understanding of local evolutionary characteristics of influenza B strains.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Infection, Genetics and Evolution, 81, art.no.104264; 2020", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier B.V."}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.meegid.2020.104264", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/)."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "15671348", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yoshihara, Keisuke"}], "nameIdentifiers": [{"nameIdentifier": "3031", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Minh, Le Nhat"}], "nameIdentifiers": [{"nameIdentifier": "3032", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okada, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "3033", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Toizumi, Michiko"}], "nameIdentifiers": [{"nameIdentifier": "3034", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nguyen, Hien Anh"}], "nameIdentifiers": [{"nameIdentifier": "3035", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Vo, Hien Minh"}], "nameIdentifiers": [{"nameIdentifier": "3036", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hashizume, Masahiro"}], "nameIdentifiers": [{"nameIdentifier": "3037", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Dang, Duc Anh"}], "nameIdentifiers": [{"nameIdentifier": "3038", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kimura, Hirokazu"}], "nameIdentifiers": [{"nameIdentifier": "3039", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshida, Lay-Myint"}], "nameIdentifiers": [{"nameIdentifier": "3040", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-18"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "IGE81_104264.pdf", "filesize": [{"value": "2.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2000000.0, "url": {"label": "IGE81_104264.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/589/files/IGE81_104264.pdf"}, "version_id": "eb4ad2ac-c444-4204-8430-84c5a725bf39"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "ARI", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Influenza B", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Molecular evolution", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Paediatric infectious disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Phylogenetic", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Vietnam", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Evolutionary dynamics of influenza B strains detected from paediatric acute respiratory infections in central Vietnam", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Evolutionary dynamics of influenza B strains detected from paediatric acute respiratory infections in central Vietnam"}]}, "item_type_id": "2", "owner": "2", "path": ["36"], "permalink_uri": "http://hdl.handle.net/10069/39759", "pubdate": {"attribute_name": "公開日", "attribute_value": "2020-03-30"}, "publish_date": "2020-03-30", "publish_status": "0", "recid": "589", "relation": {}, "relation_version_is_last": true, "title": ["Evolutionary dynamics of influenza B strains detected from paediatric acute respiratory infections in central Vietnam"], "weko_shared_id": -1}
Evolutionary dynamics of influenza B strains detected from paediatric acute respiratory infections in central Vietnam
http://hdl.handle.net/10069/39759
http://hdl.handle.net/10069/39759a9b8dce0-3d8e-47e7-8870-6d3b61ec9650
名前 / ファイル | ライセンス | アクション |
---|---|---|
IGE81_104264.pdf (2.0 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2020-03-30 | |||||
タイトル | ||||||
タイトル | Evolutionary dynamics of influenza B strains detected from paediatric acute respiratory infections in central Vietnam | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ARI | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Influenza B | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Molecular evolution | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Paediatric infectious disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Phylogenetic | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Vietnam | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yoshihara, Keisuke
× Yoshihara, Keisuke× Minh, Le Nhat× Okada, Takashi× Toizumi, Michiko× Nguyen, Hien Anh× Vo, Hien Minh× Hashizume, Masahiro× Dang, Duc Anh× Kimura, Hirokazu× Yoshida, Lay-Myint |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Influenza virus B belongs to the family Orthomyxoviridae with segmented negative-sense RNA genomes. Since 1970s, influenza B has diverged intoVictoria and Yamagata, which differs in antigenic and evolutionary characteristics. Yet, molecular-epidemiological information of influenza B from developing nations is limited. In central Vietnam, influenza A subtype-specific circulation pattern and clinical characteristics were previously described. However, molecular evolutionary characteristics of influenza B has not been discussed to date. We utilized the influenza B positives obtained from paediatric ARI surveillance during 2007?2013. Influenza B HA and NA genes were amplified, sequenced, and phylogenetic/molecular evolutionary analysis was performed using Maximum Likelihood and Bayesian MCMC. Phylodynamics analysis was performed with Bayesian Skyline Plot (BSP). Furthermore, we performed selection pressure analysis and estimated N-glycosylation sites. In the current study, overall positive rate for influenza B was 3.0%, and Victoria lineage immediately became predominant in post-A/H1N1pdm09 period. The noticeable shift in Victoria lineage WHO Group occurred. With respect to the evolutionary rate (substitutions/site/year), Victoria lineage HA gene was evolving faster than Yamagata lineage (2.43 × 10?3 vs 2.00 × 10?3). Furthermore, the evolutionary rate of Victoria Group 5 was greater than Group 1. BSP presented the rapid growth in Effective Population Size (EPS) of Victoria lineage occurred soon after the 1st A/H1N1pdm09 case was detected whereas the EPS of Yamagata lineage was stable for both genes. N-glycosylation pattern between lineages and among WHO Groups were slightly different, and HA gene had a total of 6 amino acid substitutions under positive section pressure (4 for Victoria and 2 for Yamagata). The current results highlight the importance of Victoria lineage in post-A/H1N1pdm09 period. Difference in evolutionary characteristics and phylodynamics may indicate lineage and WHO Group-specific evolutionary dynamics. It is necessary to further continue the molecular-epidemiological surveillance in local setting to gain a better understanding of local evolutionary characteristics of influenza B strains. | |||||
書誌情報 |
Infection, Genetics and Evolution 巻 81, p. 104264, 発行日 2020-02-24 |
|||||
出版者 | ||||||
出版者 | Elsevier B.V. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 15671348 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.meegid.2020.104264 | |||||
権利 | ||||||
権利情報 | c 2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Infection, Genetics and Evolution, 81, art.no.104264; 2020 |