Distinguishing true coagulase-negative staphylococci bacteremia from contamination remains a challenge. We conducted a retrospective analysis of 183 patients with methicillin-resistant coagulase-negative staphylococci (MR-CoNS)-positive and methicillin-resistant Staphylococcus aureus-positive cultures obtained from sterile sites such as blood, synovial fluid, ascitic fluid, and cerebrospinal fluid. Of the 209 MR-CoNS isolates, 83 (39.7%) were considered infection associated, and 126 (60.3%) were considered contamination. MR-CoNS isolates cultured from synovial fluid were more likely to be infection associated (. P= 0.009). The median interval from insertion of a central venous catheter to onset of infection tended to be longer in MR-CoNS infection cases than in methicillin-resistant S. aureus infection cases (41 days versus 14 days, P= 0.055). In conclusion, our results suggest that the proportion of cases of true MR-CoNS infection may be higher than previously reported
雑誌名
Diagnostic Microbiology and Infectious Disease
巻
81
号
1
ページ
71 - 75
発行年
2015-01
出版者
Elsevier Inc.
ISSN
07328893
DOI
10.1016/j.diagmicrobio.2014.09.019
権利
c 2015 Elsevier Inc.
NOTICE: this is the author’s version of a work that was accepted for publication in Diagnostic Microbiology and Infectious Disease. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Diagnostic Microbiology and Infectious Disease, 81, 1, (2015)
著者版フラグ
author
引用
Diagnostic Microbiology and Infectious Disease, 81(1), pp.71-75; 2015
Clinical significance of methicillin-resistant coagulase-negative staphylococci obtained from sterile specimens
DMID81_71.pdf
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