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Species identification, antifungal susceptibility, and clinical feature association of Aspergillus section Nigri isolates from the lower respiratory tract
http://hdl.handle.net/10069/39834
http://hdl.handle.net/10069/398349cfffa19-32fa-4602-b693-f432e5ba5a43
名前 / ファイル | ライセンス | アクション |
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MedMyc58_310.pdf (426.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-06-26 | |||||
タイトル | ||||||
タイトル | Species identification, antifungal susceptibility, and clinical feature association of Aspergillus section Nigri isolates from the lower respiratory tract | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Aspergillus section Nigri | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | colonization | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pulmonary aspergillosis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kamei, Katsuhiko
× Kamei, Katsuhiko× Tohma, Shigeto× Matsui, Hirotoshi× Nagai, Hideaki× Tamura, Atsuhisa× Yamane, Akira× Masuda, Kimihiko× Fukami, Takeshi× Ohshima, Nobuharu× Kawashima, Masahiro× Shimada, Masahiro× Akashi, Shunsuke× Inoue, Eri× Higa, Katsuyuki× Matsuki, Mei× Watanabe, Akira× Suzuki, Junko× Takeda, Keita |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Species of Aspergillus section Nigri are generally identified by molecular genetics approaches, whereas in clinical practice, they are classified as A. niger by their morphological characteristics. This study aimed to investigate whether the species of Aspergillus section Nigri isolated from the respiratory tract vary depending on clinical diagnosis. Forty-four Aspergillus section Nigri isolates isolated from the lower respiratory tracts of 43 patients were collected from February 2012 to January 2017 at the National Hospital Organization (NHO) Tokyo National Hospital. Species identification was carried out based on β-tubulin gene analysis. Drug susceptibility tests were performed according to the Clinical and Laboratory Standards Institute (CLSI) M38 3rd edition, and the clinical characteristics were retrospectively reviewed. A. welwitschiae was isolated most frequently, followed by A. tubingensis. More than half of the A. tubingensis isolates exhibited low susceptibility to azoles in contrast to only one A. welwitschiae isolate. Approximately three quarters of the patients from whom A. welwitschiae was isolated were diagnosed with colonization, whereas more than half the patients from whom A. tubingensis was isolated were diagnosed with chronic pulmonary aspergillosis (CPA). More attention needs to be given to the drug choice for patients with CPA with Aspergillus section Nigri infection because A. tubingensis, which was found to be frequently azole-resistant, was the most prevalent in these patients. | |||||
書誌情報 |
Medical Mycology 巻 58, 号 3, p. 310-314, 発行日 2019-06-26 |
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出版者 | ||||||
出版者 | Oxford University Press | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13693786 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 14602709 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1093/mmy/myz072 | |||||
権利 | ||||||
権利情報 | c The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Medical mycology, 58(3), pp.310-314; 2020 |