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Functional characterization of the regulators of calcineurin in Candida glabrata
http://hdl.handle.net/10069/27451
http://hdl.handle.net/10069/274516647fb4a-fefb-43f0-a14a-a00aef8b0655
名前 / ファイル | ライセンス | アクション |
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FEMS11_621.pdf (1.1 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-01-01 | |||||
タイトル | ||||||
タイトル | Functional characterization of the regulators of calcineurin in Candida glabrata | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Antifungal resistance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Crz1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rcn1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rcn2 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Miyazaki, Taiga
× Miyazaki, Taiga× Izumikawa, Koichi× Nagayoshi, Yohsuke× Saijo, Tomomi× Yamauchi, Shunsuke× Morinaga, Yoshitomo× Seki, Masafumi× Kakeya, Hiroshi× Yamamoto, Yoshihiro× Yanagihara, Katsunori× Miyazaki, Yoshitsugu× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The serine-threonine-specific protein phosphatase calcineurin is a key mediator of various stress responses in fungi. Herein, we characterized functions of the endogenous regulators of calcineurin (RCNs), Rcn1 and Rcn2, in the pathogenic fungus Candida glabrata. Rcn1 exerted both inhibitory and stimulatory effects on calcineurin signaling, but Rcn2 displayed only inhibitory activity. Phenotypic analyses of C. glabrata strains lacking either RCNs, calcineurin, or both revealed that calcineurin requires Rcn1, but not Rcn2, for antifungal tolerance in C. glabrata. | |||||
書誌情報 |
FEMS Yeast Research 巻 11, 号 8, p. 621-630, 発行日 2011-12 |
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出版者 | ||||||
出版者 | Blackwell Publishing Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 15671356 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 15671364 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11577311 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1111/j.1567-1364.2011.00751.x | |||||
権利 | ||||||
権利情報 | © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. | |||||
権利 | ||||||
権利情報 | The definitive version is available at www.blackwell-synergy.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | FEMS Yeast Research, 11(8), pp.621-630; 2011 |