WEKO3
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Successful treatment of sepsis-induced disseminated intravascular coagulation in a patient with idiopathic thrombocytopenic purpura using recombinant human soluble thrombomodulin
http://hdl.handle.net/10069/27963
http://hdl.handle.net/10069/279634c583264-597e-4047-a876-e4fca3d5ba8f
名前 / ファイル | ライセンス | アクション |
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PheInt31_1657.pdf (474.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2012-03-05 | |||||
タイトル | ||||||
タイトル | Successful treatment of sepsis-induced disseminated intravascular coagulation in a patient with idiopathic thrombocytopenic purpura using recombinant human soluble thrombomodulin | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Disseminated intravascular coagulation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Idiopathic thrombocytopenic purpura | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Recombinant human soluble thrombomodulin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Sepsis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Koga, Tomohiro
× Koga, Tomohiro× Inoue, Daisuke× Okada, Akitomo× Aramaki, Toshiyuki× Yamasaki, Satoshi× Nakashima, Munetoshi× Kawakami, Atsushi× Eguchi, Katsumi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Disseminated intravascular coagulation (DIC) may complicate a variety of disorders that contribute to mortality, particularly those related to bleeding. It is therefore very difficult to manage DIC in patients with known bleeding disorders. We treated a 62-year-old woman with idiopathic thrombocytopenic purpura (ITP) complicated with sepsis-induced DIC. She had been diagnosed with ITP 8 months prior to admission. Laboratory tests showed an elevation of d-dimer and endotoxin, while pyelonephritis was shown by abdominal computed tomography. Escherichia coli was detected by blood culture. Based on these findings, the patient was diagnosed with sepsis-induced DIC due to urinary tract infection. Thrombocytopenia was refractory despite the use of antibiotics and platelet transfusion, but it was promptly improved in response to recombinant human soluble thrombomodulin (rTM). We suggest that rTM provides a new therapeutic strategy for DIC patients with high hemorrhagic risk. | |||||
書誌情報 |
Rheumatology International 巻 31, 号 12, p. 1657-1659, 発行日 2011-12 |
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出版者 | ||||||
出版者 | Springer Verlag | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 01728172 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1437160X | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA0040456X | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s00296-010-1754-1 | |||||
権利 | ||||||
権利情報 | © Springer-Verlag 2011 | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Rheumatology International, 31(12), pp.1657-1659 |