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Low Glomerular Filtration Rate Is Associated With High Prevalence of Vasospastic Angina
http://hdl.handle.net/10069/25611
http://hdl.handle.net/10069/25611c0052e88-ecee-4aff-aa8e-92c77945d1e5
名前 / ファイル | ライセンス | アクション |
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CirJou75_1691.pdf (649.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-08-31 | |||||
タイトル | ||||||
タイトル | Low Glomerular Filtration Rate Is Associated With High Prevalence of Vasospastic Angina | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Chronic kidney disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Coronary spasm | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Endothelial dysfunction | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Koga, Seiji
× Koga, Seiji× Ikeda, Satoshi× Nakata, Tomoo× Yasunaga, Tomohiko× Takeno, Masayoshi× Koide, Yuji× Maemura, Koji |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Although chronic kidney disease is associated with a high prevalence of cardiovascular disease, the relationship between coronary artery spasm and renal dysfunction has not been elucidated. Methods and Results: We evaluated 139 patients with chest pain at rest who had no significant organic stenosis on coronary angiograms and who underwent coronary spasm provocation tests using acetylcholine or ergonovine. The results of the provocation tests revealed that 59 patients had vasospastic angina (VSA), and that 80 did not (non-VSA). We analyzed the association between VSA and renal dysfunction using the estimated glomerular filtration rate (eGFR). The eGFR was significantly lower in the VSA group than in the non-VSA group (P=0.013). The patients were assigned to quartiles (Q) 1, 2, 3 and 4 based on eGFR (ml·min-1·1.73 m2) <64.1, 64.1-74.7, 74.8-85.0 and ≥85.1, respectively, in each of which the prevalence of VSA was 57%, 53%, 34% and 26%, respectively. The prevalence of VSA was significantly higher in Q1 than in Q4 (P=0.008). Logistic regression analysis showed that the independent factors associated with the presence of VSA were a lower eGFR (P=0.011) and male gender (P=0.001). Conclusions: Lower levels of eGFR in our study population were significantly and independently associated with a high prevalence of VSA, suggesting that a lower eGFR could be a risk factor for VSA. | |||||
書誌情報 |
Circulation Journal 巻 75, 号 7, p. 1691-1695, 発行日 2011-06-24 |
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出版者 | ||||||
出版者 | The Japanese Circulation Society | |||||
出版者別言語 | ||||||
日本循環器学会 | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13469843 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13474820 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11591968 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1253/circj.CJ-10-0864 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2011 THE JAPANESE CIRCULATION SOCIETY | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Circulation Journal, 75(7), pp.1691-1695; 2011 |