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Response Properties of Nucleus Reticularis Lateralis Neurons After Electroacupuncture Stimulation in Rats
http://hdl.handle.net/10069/24047
http://hdl.handle.net/10069/24047bf84be3a-1263-4be9-831e-bc1ef7bbef74
名前 / ファイル | ライセンス | アクション |
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AJCM38_869.pdf (680.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-10-01 | |||||
タイトル | ||||||
タイトル | Response Properties of Nucleus Reticularis Lateralis Neurons After Electroacupuncture Stimulation in Rats | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Electroacupuncture | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Nucleus Raphe Magnus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Nucleus Reticularis Lateralis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pain | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rat | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Spinal Cord | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Moritaka, Kentaro
× Moritaka, Kentaro× Zeredo, Jorge L.× Kimoto, Mari× Nasution, Fajar H.× Hirano, Takafumi× Toda, Kazuo |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A descending inhibitory mechanism from the periaqueductal gray (PAG) to the spinal cord through the nucleus raphe magnus (NRM) is strongly involved in endogenous analgesic system produced by acupuncture stimulation. In addition to the PAG to NRM system which descends in the medial pathway of the brain stem, the nucleus reticularis lateralis (NRL) situated in the lateral part of the brain stem is reported to play an important role in modulating centrifugal antinociceptive action. In the present study, to clarify the role of NRL in acupuncture analgesia, we investigated the response properties of NRL neurons to acupuncture stimulation. The majority of NRM-projecting NRL neurons were inhibited by electroacupuncture stimulation. This effect was antagonized by ionophoretic application of naloxone, indicating that endogenous opioids act directly onto these NRL neurons. By contrast, about half of spinal projecting NRL neurons were excited by electroacupuncture stimulation, suggesting that part of the NRL neurons may modulate pain transmission directly at the spinal level. | |||||
書誌情報 |
The American Journal of Chinese Medicine 巻 38, 号 5, p. 869-880, 発行日 2010 |
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出版者 | ||||||
出版者 | World Scientific Publishing | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0192415X | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00066285 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1142/S0192415X10008317 | |||||
権利 | ||||||
権利情報 | Electronic version of an article published as The American Journal of Chinese Medicine, 38(5), pp.869-880; 2010. http://dx.doi.org/10.1142/S0192415X10008317. © 2010 World Scientific Publishing Company & Institute for Advanced Research in Asian Science and Medicine. http://www.worldscinet.com/ajcm/38/3805/S0192415X10008317.html | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | The American Journal of Chinese Medicine, 38(5), pp.869-880; 2010 |