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Evaluation of Surgical Resection for Ampullar Carcinoma at Japanese Single Cancer Institute
http://hdl.handle.net/10069/24158
http://hdl.handle.net/10069/241589b2f68fb-8c6e-47ad-a5af-2d950caf8602
名前 / ファイル | ライセンス | アクション |
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ActaMed55_23.pdf (110.6 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-10-08 | |||||
タイトル | ||||||
タイトル | Evaluation of Surgical Resection for Ampullar Carcinoma at Japanese Single Cancer Institute | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Ampullar carcinoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pancreaticoduodenectomy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Radical operation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Nanashima, Atsushi
× Nanashima, Atsushi× Tobinaga, Syuuichi× Abo, Takafumi× Ohnita, Ken× Norimura, Daisuke× Yajima, Hiroyuki× Takeshita, Hiroaki× Onaka, Takashi× Hidaka, Shigekazu× Takeshima, Fuminao× Yamaguchi, Naoyuki× Isomoto, Hajime× Sawai, Terumitsu× Nakao, Kazuhiko× Nagayasu, Takeshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Surgical resection is the only radical treatment option for duodenal ampullar carcinoma (AC) that results in an improved patient prognosis. Method: We examined the demographics, surgical records, and outcome in 23 patients with AC undergoing pancreaticoduodenectomy (PD). Results: Of 23 patients, 17 underwent pylorus preserving PD (PPPD) and 6 underwent PD, including subtotal stomach-preserving PD in 5. D2 lymphadenectomy was performed in 17 patients and D3 lymphadenectomy was performed in 6. The combined resection of the superior mesenteric vein was performed in 1 patient. Postoperative cancer recurrence was observed in 32%, and 6 patients died of cancer. The 3-year tumor-free survival rates were not different between the final stages (p=0.64) and the 5-year cancer-related overall survival rates were not different between stages either (p=0.28). Tumor size?3cm resulted in significantly poorer survival rate compared to smaller tumors (p=0.032). Node metastasis at Group 2, and moderately or poorly differentiated adenocarcinoma were significantly associated with poor survival (p<0.05); however, cancer infiltration at cut-end margin, degree of node dissection and curability were not associated with overall prognosis. Conclusions: Radical surgical resection showed good patient prognosis; however, new adjuvant chemotherapy is a promising modality to improve patient survival in AC patients with poor prognostic factors. | |||||
書誌情報 |
Acta Medica Nagasakiensia 巻 55, 号 1, p. 23-28, 発行日 2010-08 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
長崎大学医学部 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta Medica Nagasakiensia, 55(1), pp.23-28; 2010 |