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生体適合性ヒドロゲルへのリボソームのカプセル化
http://hdl.handle.net/10069/24219
http://hdl.handle.net/10069/24219c4558f9b-9908-4faa-a92a-527c2fe7041c
名前 / ファイル | ライセンス | アクション |
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kogaku16_27_13.pdf (2.6 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-10-14 | |||||
タイトル | ||||||
タイトル | 生体適合性ヒドロゲルへのリボソームのカプセル化 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
佐藤, 智典
× 佐藤, 智典× 武居, 智× 砂本, 順三 |
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著者別名 | ||||||
姓名 | Sato, Toshinori | |||||
著者別名 | ||||||
姓名 | Takei, Satoshi | |||||
著者別名 | ||||||
姓名 | Sunamoto, Junzo | |||||
その他のタイトル | ||||||
その他のタイトル | Effective Encapsulation of Uposomes by Biocompatible Hydrogels | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | An improved technique has been newly developed in order to overcome essential disadvantages of liposome and hydrogel each other in the biotechnological utilization. This methodology involves the encapsulation of egg lecithin liposome by such an appropriate hydrogel that does not give any serious damage to the liposome during the encapsulation procedure. Of various hydrogels, the copolymer of acrylic acid with vinylalcohol or vinylacetate seemed to be the best candidate for the present purpose. Interactions between liposomes and hydro gels were investigated from three aspects : (1) spontaneous leakage of a water soluble fluorescent probe, carboxyfluorescein, as doubly encapsulated in liposome-hydrogel ; (2) distribution of liposomes between bulk water phase and hydrogel, which was determined by monitoring an increase in the fluorescent intensity of diphenylhexatriene, DPH, as encapsulated in the liposomal membrane ; and (3) retarded lip oxygenase peroxidation of linoleic acid as embedded in the liposomal membrane. Through all the investigations, the encapsulation of liposome into hydrogel seemed to be a suitable technique applicable to the serum free mammalian cell culture and implantation in vivo as the biomedical material. | |||||
書誌情報 |
長崎大学工学部研究報告 en : Reports of the Faculty of Engineering, Nagasaki University 巻 16, 号 27, p. 183-192, 発行日 1986-07 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 02860902 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18805574 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00178418 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 長崎大学工学部 | |||||
出版者別言語 | ||||||
Faculty of Engineering, Nagasaki University | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 長崎大学工学部研究報告, 16(27), pp.183-192; 1986 |