WEKO3
アイテム
{"_buckets": {"deposit": "1e2fc10a-8d5e-4a75-a40c-df6cb8d946cb"}, "_deposit": {"created_by": 2, "id": "14546", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "14546"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00014546", "sets": ["36"]}, "author_link": ["53404", "53402", "53405", "53403", "53401", "53400"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "396", "bibliographicPageStart": "391", "bibliographicVolumeNumber": "72", "bibliographic_titles": [{"bibliographic_title": "Journal of Veterinary Medical Science"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Tick-borne encephalitis virus (TBEV) is a zoonotic agent that causes acute central nervous system (CNS) disease in humans. In this study, we examined the pathogenic process following intracerebral infection with the Oshima strain of TBEV in a mouse model. Intracerebral infection resulted in dose-dependent mortality, and all mice died following challenge with 102 PFU or more of the virus within 10 days. Acutely necrotic neurons and widespread inflammation were observed throughout the CNS. We therefore conclude that mortality following intracerebral infection results from a direct CNS pathology.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Journal of Veterinary Medical Science, 72(4), pp.391-396; 2010", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Japanese Society of Veterinary Science"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1292/jvms.09-0258", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright(c) 2010 by the Japanese Society of Veterinary Science"}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10796138", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "09167250", "subitem_source_identifier_type": "ISSN"}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "13477439", "subitem_source_identifier_type": "ISSN"}]}, "item_2_text_62": {"attribute_name": "出版者別言語", "attribute_value_mlt": [{"subitem_text_value": "日本獣医学会"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Hayasaka, Daisuke"}], "nameIdentifiers": [{"nameIdentifier": "53400", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagata, Noriyo"}], "nameIdentifiers": [{"nameIdentifier": "53401", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hasegawa, Hideki"}], "nameIdentifiers": [{"nameIdentifier": "53402", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sata, Tetsutaro"}], "nameIdentifiers": [{"nameIdentifier": "53403", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takashima, Ikuo"}], "nameIdentifiers": [{"nameIdentifier": "53404", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koike, Satoshi"}], "nameIdentifiers": [{"nameIdentifier": "53405", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "JVMS72_391.pdf", "filesize": [{"value": "695.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 695500.0, "url": {"label": "JVMS72_391.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/14546/files/JVMS72_391.pdf"}, "version_id": "7b6a5c49-9913-4a34-9dd3-33e118db5dec"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Central nervous system", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Mouse", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Pathogenesis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Tick-borne disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Virus infection", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model"}]}, "item_type_id": "2", "owner": "2", "path": ["36"], "permalink_uri": "http://hdl.handle.net/10069/24538", "pubdate": {"attribute_name": "公開日", "attribute_value": "2010-12-21"}, "publish_date": "2010-12-21", "publish_status": "0", "recid": "14546", "relation": {}, "relation_version_is_last": true, "title": ["Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model"], "weko_shared_id": 2}
Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model
http://hdl.handle.net/10069/24538
http://hdl.handle.net/10069/245381ae70cc1-e98e-4d9c-b4ec-e4062a1bd93a
名前 / ファイル | ライセンス | アクション |
---|---|---|
JVMS72_391.pdf (695.5 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2010-12-21 | |||||
タイトル | ||||||
タイトル | Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Central nervous system | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mouse | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pathogenesis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tick-borne disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Virus infection | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Hayasaka, Daisuke
× Hayasaka, Daisuke× Nagata, Noriyo× Hasegawa, Hideki× Sata, Tetsutaro× Takashima, Ikuo× Koike, Satoshi |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Tick-borne encephalitis virus (TBEV) is a zoonotic agent that causes acute central nervous system (CNS) disease in humans. In this study, we examined the pathogenic process following intracerebral infection with the Oshima strain of TBEV in a mouse model. Intracerebral infection resulted in dose-dependent mortality, and all mice died following challenge with 102 PFU or more of the virus within 10 days. Acutely necrotic neurons and widespread inflammation were observed throughout the CNS. We therefore conclude that mortality following intracerebral infection results from a direct CNS pathology. | |||||
書誌情報 |
Journal of Veterinary Medical Science 巻 72, 号 4, p. 391-396, 発行日 2010-04 |
|||||
出版者 | ||||||
出版者 | Japanese Society of Veterinary Science | |||||
出版者別言語 | ||||||
日本獣医学会 | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09167250 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13477439 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10796138 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1292/jvms.09-0258 | |||||
権利 | ||||||
権利情報 | Copyright(c) 2010 by the Japanese Society of Veterinary Science | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Veterinary Medical Science, 72(4), pp.391-396; 2010 |