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Age-related changes in bone density, geometry and biomechanical properties of the proximal femur: CT-based 3D hip structure analysis in normal postmenopausal women.
http://hdl.handle.net/10069/24600
http://hdl.handle.net/10069/246001e3fb740-912e-40ea-8fb4-db66ec839c96
名前 / ファイル | ライセンス | アクション |
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Bone48_627.pdf (393.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-02-07 | |||||
タイトル | ||||||
タイトル | Age-related changes in bone density, geometry and biomechanical properties of the proximal femur: CT-based 3D hip structure analysis in normal postmenopausal women. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bone mineral density (BMD) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Computed tomography (CT) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hip geometry | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Osteoporosis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ito, Masako
× Ito, Masako× Nakata, Tomoko× Nishida, Akifumi× Uetani, Masataka |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The geometry as well as bone mineral density (BMD) of the proximal femur contributes to fracture risk. How and the extent to which they change due to natural aging is not fully understood. We assessed BMD and geometry in the femoral neck and shaft separately, in 59 normal Japanese postmenopausal women aged 54-84years, using clinical computed tomography (CT) and commercially available software, at baseline and 2-year follow-up. This system detected significant reductions over the 2-year interval in total BMD (%change/year=-0.900±0.257, p<0.0005), cortical cross-sectional area (CSA) (-0.800±0.423%/year, p<0.05) and cortical thickness (-1.120±0.453%/year, p<0.01) in the femoral neck. In the femoral shaft, cortical BMD decreased significantly (-0.642±0.188%/year, p<0.005). Regarding biomechanical parameters in the femoral neck, the cross-sectional moment of inertia (CSMI) and section modulus (SM) decreased (-1.38±3.65%/year, p<0.01 and -1.37±2.96%/year, p<0.005) and the buckling ratio (BR) increased significantly (1.48±4.81%/year, p<0.05), whereas no changes were found in the femoral shaft. The distinct patterns of age-related changes in the geometry and biomechanical properties in the femoral neck and shaft suggest that improved geometric measures are possible with the current non-invasive method using clinical CT. | |||||
書誌情報 |
Bone 巻 48, 号 3, p. 627-630, 発行日 2010-03-01 |
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出版者 | ||||||
出版者 | Elsevier Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 87563282 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18732763 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10506985 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 21087686 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.bone.2010.11.007 | |||||
権利 | ||||||
権利情報 | Copyright © 2010 Elsevier Inc. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Bone, 48(3), pp.627-630; 2011 |