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Screening Validity of Arterial Pressure?Volume Index and Arterial Velocity?Pulse Index for Preclinical Atherosclerosis in Japanese Community-Dwelling Adults: the Nagasaki Islands Study
http://hdl.handle.net/10069/38736
http://hdl.handle.net/10069/38736dee77631-4e61-4b3e-8d24-0ba703ea7c5e
名前 / ファイル | ライセンス | アクション |
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JAT25_792.pdf (212.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-12-18 | |||||
タイトル | ||||||
タイトル | Screening Validity of Arterial Pressure?Volume Index and Arterial Velocity?Pulse Index for Preclinical Atherosclerosis in Japanese Community-Dwelling Adults: the Nagasaki Islands Study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Arterial pressure-volume index | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Arterial stiffness | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Arterial velocity-pulse index | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Carotid intima-media thickness | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yamanashi, Hirotomo
× Yamanashi, Hirotomo× Koyamatsu, Jun× Nagayoshi, Mako× Shimizu, Yuji× Kawashiri, Shin-ya× Kondo, Hideaki× Fukui, Shoichi× Tamai, Mami× Maeda, Takahiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Aim: The arterial pressure?volume index (API) and arterial velocity?pulse index (AVI) are novel measurement indices of arterial stiffness. This study was performed to examine the screening validity of the API and AVI for preclinical atherosclerosis in Japanese community-dwelling adults. Methods: We conducted a cross-sectional study of 2,809 participants aged ?40 years who underwent Japanese national medical check-ups from 2014 to 2016. Preclinical atherosclerosis was defined as a mean carotid intima?media thickness (CIMT) of ? 1.0 mm. Multivariable linear regression analysis was performed to investigate the association of CIMT with API and AVI, adjusting for body mass index, sex, and the Framingham ?D'Agostino score. We also examined receiver operating characteristic curves, sensitivity, and specificity to predict preclinical atherosclerosis defined by the CIMT. The cardio-ankle vascular index was also measured for comparison with the API and AVI. Results: Of 2,809 participants, 68 (2.4%) had preclinical atherosclerosis. In the multivariable linear regression analysis, the API and AVI maintained a positive association with the mean CIMT (B =2.6, P =0.009 and B =3.7, P =0.001, respectively). The cut-offs of the API and AVI that demonstrated better sensitivity and specificity for detection of subclinical atherosclerosis were 31 [area under the curve (AUC), 0.64] and 29 (AUC, 0.60). Conclusions: The API and AVI were positively associated with preclinical carotid atherosclerosis independent of the participants' cardiovascular risk. The ability of these scores to predict carotid atherosclerosis could make them a useful screening tool for atherosclerosis. | |||||
書誌情報 |
Journal of Atherosclerosis and Thrombosis 巻 25, 号 9, p. 792-798, 発行日 2018-09-01 |
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出版者 | ||||||
出版者 | 日本動脈硬化学会 | |||||
出版者別言語 | ||||||
Japan Atherosclerosis Society | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13403478 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18803873 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.5551/jat.43125 | |||||
権利 | ||||||
権利情報 | c 2018 Japan Atherosclerosis Society. This article is distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Atherosclerosis and Thrombosis, 25(9), pp.792-798; 2018 |