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Recent progress in bone imaging for osteoporosis research.
http://hdl.handle.net/10069/24840
http://hdl.handle.net/10069/248406fa5d35e-dedc-48ae-9b4a-18f8055872f1
名前 / ファイル | ライセンス | アクション |
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JBMM29_131.pdf (2.1 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-04-01 | |||||
タイトル | ||||||
タイトル | Recent progress in bone imaging for osteoporosis research. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Computed tomography | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Finite element model | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Geometry | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Magnetic resonance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Microstructure | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ito, Masako
× Ito, Masako |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Advances in bone imaging techniques have provided tools for analyzing bone structure at the macro-, micro- and nano-level. Quantitative assessment of macrostructure can be achieved using dual X-ray absorptiometry (DXA) and quantitative computed tomography (QCT), particularly volumetric quantitative CT (vQCT). In vivo quantitative techniques for assessing the microstructure of trabecular bone non-invasively and non-destructively include high-resolution CT (HR-CT) and high-resolution magnetic resonance (HR-MR). Compared with MR imaging, CT-based techniques have the advantage of directly visualizing the bone in the axial skeleton, with high spatial resolution, but the disadvantage of delivering a considerable radiation dose. Micro-CT (μCT), which provides a higher resolution of the microstructure and is principally applicable in vitro, has undergone technological advances such that it is now able to elucidate the physiological skeletal change mechanisms associated with aging and determine the effects of therapeutic intervention on the bone microstructure. In particular, synchrotron μCT (SR-CT) provides a more detailed view of trabecular structure at the nano-level. For the assessment of hip geometry, DXA-based hip structure analysis (HSA) and CT-based HSA have been developed. DXA-based HSA is a convenient tool for analyzing biomechanical properties and for assuming cross-sectional hip geometry based on two-dimensional (2D) data, whereas CT-based HSA provides these parameters three-dimensionally in robust relationship with biomechanical properties, at the cost of greater radiation exposure and the lengthy time required for the analytical procedure. Further progress in bone imaging technology is promising to bring new aspects of bone structure in relation to bone strength to light, and to establish a means for analyzing bone structural properties in the everyday clinical setting. | |||||
書誌情報 |
Journal of bone and mineral metabolism 巻 29, 号 2, p. 131-140, 発行日 2011-03 |
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出版者 | ||||||
出版者 | Springer Verlag | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09148779 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 14355604 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10747551 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 21301898 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s00774-010-0258-0 | |||||
権利 | ||||||
権利情報 | © The Japanese Society for Bone and Mineral Research and Springer 2011 | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of bone and mineral metabolism, 29(2), pp.131-140; 2011 |