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A Retrospective Epidemiological Study of Tick-Borne Encephalitis Virus in Patients with Neurological Disorders in Hokkaido, Japan
http://hdl.handle.net/10069/40384
http://hdl.handle.net/10069/4038416fe0fee-e91a-47bc-81fe-7fc7249c245f
名前 / ファイル | ライセンス | アクション |
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Micoorganizms8_1672.pdf (220.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-11-12 | |||||
タイトル | ||||||
タイトル | A Retrospective Epidemiological Study of Tick-Borne Encephalitis Virus in Patients with Neurological Disorders in Hokkaido, Japan | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epidemiology | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Neurological disorder | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tick | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tick-borne encephalitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Zoonosis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yoshii, Kentaro
× Yoshii, Kentaro× Takahashi-Iwata, Ikuko× Shirai, Shinichi× Kobayashi, Shintaro× Yabe, Ichiro× Sasaki, Hidenao |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Tick-borne encephalitis (TBE) is a zoonotic disease that usually presents as a moderate febrile illness followed by severe encephalitis, and various neurological symptoms are observed depending on the distinct central nervous system (CNS) regions affected by the TBE virus (TBEV) infection. In Japan, TBE incidence is increasing and TBEV distributions are reported in wide areas, specifically in Hokkaido.However, an extensive epidemiological survey regarding TBEV has not been conducted yet. In this study, we conducted a retrospective study of the prevalence of antibodies against TBEV in patients with neurological disorders and healthy populations in a TBEV-endemic area in Hokkaido. Among 2000 patients, three patients with inflammatory diseases in the CNS had TBEV-specific IgM antibodies and neutralizing antibodies. The other four patients diagnosed clinically with other neurological diseases were positive for TBEV-specific IgG and neutralizing antibodies, indicating previous TBEV infection. In a total of 246 healthy residents in a TBEV-endemic region, one resident had TBEV-specific antibodies. These results demonstrated undiagnosed TBEV infections in Japan. Further surveys are required to reveal the actual epidemiological risk of TBE and to consider preventive measures, such as a vaccine program, for the control of TBE in Japan. |
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書誌情報 |
Microorganisms 巻 8, 号 11, p. 1672, 発行日 2020-10-28 |
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出版者 | ||||||
出版者 | MDPI | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 20762607 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/microorganisms8111672 | |||||
権利 | ||||||
権利情報 | c 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open accessarticle distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/) | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Microorganisms, 8(11), art.no.1672, ; 2020 |