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COMPARATIVE STUDIES BETWEEN HORMONE CONTENTS AND MORPHOLOGICAL APPEARANCES IN HUMAN ADRENAL CORTEX
http://hdl.handle.net/10069/23450
http://hdl.handle.net/10069/234507532f089-79e5-477f-ab93-8922d1ec3380
名前 / ファイル | ライセンス | アクション |
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AHC15_386.pdf (4.0 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-08-06 | |||||
タイトル | ||||||
タイトル | COMPARATIVE STUDIES BETWEEN HORMONE CONTENTS AND MORPHOLOGICAL APPEARANCES IN HUMAN ADRENAL CORTEX | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Shigematsu, Kazuto
× Shigematsu, Kazuto |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The hormone content in Cushing-type non-functioning tumors of the adrenal glands was measured to be compared with those of functioning adenomas. Furthermore, the relationship between the hormone contents and the proportion of clear-type cells and compact-type cells in the tissues were also studied. The contents of aldosterone and corticosterone were significantly higher in primary aldosteronism than in other groups. The cortisol content was significantly higher in Cushing's syndrome than in primary aldosteronism, but it was not statistically different from non-functioning adenomatous nodules. The patterns of hormone contents in non-functioning adenomatous nodules were similar to those in Cushing's syndrome. In primary aldosteronism, there was a positive correlation between the aldosterone content and the increase of compact-type cells. Compact-type cells revealed high activities of 3β-hydroxysteroid dehydrogenase and glucose 6-phosphate dehydrogenase. These results suggest that compact-type cells play an important role in synthesis and secretion of aldosterone in primary aldosteronism. In Cushing's syndrome, there was no significant correlation between the cortisol content and the proportion of constituting cells. The activities of 3βHSD and G6PD in both types of cells were not so different from each other. Therefore, there may be a possibility that morphological differences in the two types of constituting cells show different phases of tumor cells in Cushing's syndrome. In the non-functioning tumors, the scattered tumor cells revealed marked activities of 3βHSD and G6PD. These results suggest that the number of constituting cells of “non-functioning” tumors have some degree of endocrinologic activity. | |||||
書誌情報 |
Acta Histochemica et Cytochemica 巻 15, 号 3, p. 386-400, 発行日 1982 |
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出版者 | ||||||
出版者 | 日本組織細胞化学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00445991 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13475800 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508022 | |||||
権利 | ||||||
権利情報 | Copyright © 1982 By the Japan Society of Histochemistry and Cytochemistry | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta Histochemica et Cytochemica, 15(3), pp.386-400; 1982 |