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Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2, 4 or 5.
http://hdl.handle.net/10069/38844
http://hdl.handle.net/10069/388442fe3246b-1478-4468-ac5e-374d164e56cc
名前 / ファイル | ライセンス | アクション |
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CPB42_1658.pdf (826.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-02-21 | |||||
タイトル | ||||||
タイトル | Amino Acids and Peptides. XXIII. Leu-Enkephalin Analogs Containing a Fluorinated Amino Acid at Position 2, 4 or 5. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | opioid peptide | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fluorinated amino acid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | enkephalin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | opioid receptor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mouse vas deferens | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | guinea pig ileum | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
MAEDA, Mitsuko
× MAEDA, Mitsuko× KAWASAKI, Koichi× TAGUCHI, Takeo× KOBAYASHI, Yoshiro× YAMAMOTO, Yoshihiro× SHIMOKAWA, Kazuhiro× TAKAHASHI, Masakatsu× NAKAO, Kaoru× KANETO, Hiroshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Fluorinated analogs of Leu-enkephalin were synthesized by the solution method and the solid-phase method. The synthetic peptides were examined for opioid activities on mouse vas deferens and guinea pig ileum. Among the synthetic peptides, [D-Ala2, Leu(F3)(2R, 4S)5]enkephalin and [D-Ala2, Leu(F3)(2S, 4R)5]enkephalin exhibited potent opioid activity, and [Leu(F3)(2S, 4R)5]enkephalin exhibited high δ-receptor selectivity. | |||||
書誌情報 |
Chemical & Pharmaceutical Bulletin 巻 42, 号 8, p. 1658-1662, 発行日 1994-08-15 |
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出版者 | ||||||
出版者 | 日本薬学会 | |||||
出版者別言語 | ||||||
Pharmaceutical Society of Japan | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00092363 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13475223 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00602100 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/cpb.42.1658 | |||||
権利 | ||||||
権利情報 | c The Pharmaceutical Society of Japan | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Chemical & Pharmaceutical Bulletin, 42(8), pp.1658-1662; 1994 |