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Clinical Significance of Measuring Urinary Sulfated Bile Acids in Adult Patients with Hepatobiliary Diseases.
http://hdl.handle.net/10069/23097
http://hdl.handle.net/10069/230979025ae14-2d4c-40e5-9c37-35112a124147
名前 / ファイル | ライセンス | アクション |
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HG56_299.pdf (274.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-04-05 | |||||
タイトル | ||||||
タイトル | Clinical Significance of Measuring Urinary Sulfated Bile Acids in Adult Patients with Hepatobiliary Diseases. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Urinary sulfated bile acid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cholestasis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hepatectomy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Ascites | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Nanashima, Atsushi
× Nanashima, Atsushi× Obatake, Masayuki× Sumida, Yorihisa× Abo, Takafumi× Yamane, Yusuke× Nomura, Masahito× Inamura, Yukio× Sawai, Terumitsu× Takeshita, Hiroaki× Hidaka, Shigekazu× Yasutake, Toru× Nagayasu, Takeshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background/Aims: Measurement of urinary sulfated bile acid (USBA) level is a simple urine test that reflects the degree of cholestasis in newborns. The aim of this study was to clarify the clinical significances of this test for liver diseases in adults. Methodology: We examined the relationship between USBA level in a urine sample by enzymatic assay and clinical parameters and postoperative complications in 27 patients with hepatobiliary diseases who underwent surgical procedures between 2002 and 2007. Results: Mean USBA in all patients before surgery was 39.8 ± 64.0 μmol/L (median value was 6.6). USBA level was increased in patients with cholestasis. USBA level was significantly correlated with serum total bile acid, total bilirubin level and serum hyaluronic acid level (r=0.850, 0.602 and 0.504, respectively) (p<0.05) and, furthermore, tended to be correlated with liver-uptake ratio (LHL15) by technetium-99m galactosyl human serum albumin (99mTc-GSA) scintigraphy and alanine aminotransferase level (r=-0.469 and 0.436, respectively but not significant). USBA level tended to be associated with postoperative uncontrolled ascites (p=0.050, not significant). Postoperative USBA level by day 7 was not changed; however, USBA level in patients with cholestatic diseases was decreased Conclusions: USBA is a simple and sensitive noninvasive test for cholestasis and also useful to predict postoperative uncontrolled ascites after hepatic resections. | |||||
書誌情報 |
Hepato-Gastroenterology 巻 56, 号 90, p. 299-302, 発行日 2009-03 |
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出版者 | ||||||
出版者 | Thieme | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 01726390 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00213244 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 19579586 | |||||
権利 | ||||||
権利情報 | c H.G.E. Update Medical Publishing. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関係URI | ||||||
関連名称 | http://www.iasg.org/ | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Hepato-Gastroenterology, 56(90), pp.299-302; 2009 |