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Hybrid male sterility is caused by mitochondrial DNA deletion.
http://hdl.handle.net/10069/22201
http://hdl.handle.net/10069/222012bbbe113-650f-47d6-896f-4099f346069a
名前 / ファイル | ライセンス | アクション |
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MBR36_1365.pdf (452.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-10-01 | |||||
タイトル | ||||||
タイトル | Hybrid male sterility is caused by mitochondrial DNA deletion. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Eri15 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hybrid male sterility | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Maternal Mitochondrial DNA inheritance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mitochondrial DNA deletion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Postzygotic reproductive isolation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Spag1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Speciation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | TUNEL assay | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Hayashida, Kenji
× Hayashida, Kenji× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Although it is known that the hybrid male mouse is sterile just like any other animal's heterogametic sex, the reason why only the male germ cells are impaired has yet to be discovered. TdT-mediated dUTP nick end labeling assay using a confocal fluorescence microscope and DNA fragmentation assay of hybrid testis indicated destruction of the mitochondrial DNA (mtDNA) rather than the nuclear DNA. Previously we reported that maternal mtDNA inheritance is through selective sperm mtDNA elimination based on the sperm factor and two egg factors, and expression of these three factors was recognized in the hybrid testis. It was thereby assumed that mtDNA destruction caused by the expression of maternal mtDNA inheritance system in male germ cells is implicated in the hybrid male sterility of mice. | |||||
書誌情報 |
Molecular biology reports 巻 36, 号 6, p. 1365-1369, 発行日 2009-07 |
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出版者 | ||||||
出版者 | Springer Netherlands | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03014851 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1573-4978 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00745797 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 18649010 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s11033-008-9321-5 | |||||
権利 | ||||||
権利情報 | c 2008 Springer Science+Business Media B.V. | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Molecular biology reports, 36(6), pp.1365-1369; 2009 |