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Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients.
http://hdl.handle.net/10069/22248
http://hdl.handle.net/10069/2224891c917b0-4ed1-4ffe-a58e-9f75030f2669
名前 / ファイル | ライセンス | アクション |
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EAORL266_673.pdf (174.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-10-15 | |||||
タイトル | ||||||
タイトル | Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Airborne pollen counts | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Fexofenadine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Japanese cedar pollinosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Seasonal allergic rhinitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Treatment | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takasaki, Kenji
× Takasaki, Kenji× Enatsu, Kaori× Kumagami, Hidetaka× Takahashi, Haruo |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In Japan, information on daily Japanese cedar pollen counts is made public during pollen season. If symptom severity and treatment outcome are predictable according to these pollen counts, management of seasonal allergic rhinitis may become more precise. The aims of the study were to evaluate the relationship between airborne pollen counts, symptom severity and treatment outcome in Japanese cedar pollinosis patients. In the randomized study, patients with moderate to most severe Japanese pollinosis were treated with fexofenadine (60 mg BD) or fexofenadine and nasal corticosteroids for 2 weeks. During the same period daily airborne pollen counts were measured. A total of 105 adult patients were enrolled. No difference of treatment efficacy was seen among groups. Detailed results of efficacy and safety were previously described elsewhere. In univariate analysis, the mean cumulative amount of airborne pollen exposure for 4 days prior to the study tended to affect symptom severity (P = 0.053) and the mean cumulative amount of airborne pollen during the treatment period tended to show difference among five treatment outcome categories (P = 0.066). In multivariate analysis, the mean cumulative amount of airborne pollen exposure for 4 days prior to the study was identified as the only significant factor of symptom severity (P = 0.0327) and cumulative amount of airborne pollen during the treatment period (P = 0.027) and allergic history (P = 0.027) were significant factors of treatment outcomes. No serious adverse effect was reported during the study. The amount of airborne pollen may be predictive of both symptom severity and treatment outcome. | |||||
書誌情報 |
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 巻 266, 号 5, p. 673-676, 発行日 2009-05 |
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出版者 | ||||||
出版者 | Springer Verlag | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09374477 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1434-4726 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10746537 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 18704471 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s00405-008-0793-7 | |||||
権利 | ||||||
権利情報 | c 2008 Springer-Verlag. | |||||
権利 | ||||||
権利情報 | The original publication is available at www.springerlink.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | European archives of oto-rhino-laryngology, 266(5), pp.673-676; 2009 |