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HGF-induced capillary morphogenesis of endothelial cells is regulated by Src.
http://hdl.handle.net/10069/22289
http://hdl.handle.net/10069/22289b1b33b33-a7fb-46cf-a0a0-2b793d8a44de
名前 / ファイル | ライセンス | アクション |
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BBRC344_617.pdf (701.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-10-27 | |||||
タイトル | ||||||
タイトル | HGF-induced capillary morphogenesis of endothelial cells is regulated by Src. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hepatocyte growth factor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Endothelial cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Capillary morphogenesis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Src | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | PP2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | siRNA | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kanda, Shigeru
× Kanda, Shigeru× Kanetake, Hiroshi× Miyata, Yasuyoshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The signal transduction pathway involved in hepatocyte growth factor (HGF)-induced capillary morphogenesis of endothelial cells was investigated. HGF-induced capillary morphogenesis of the murine spleen endothelial cell line MSS31 was inhibited by a Src family kinase inhibitor, PP2. Stable expression of kinase-inactive Src in MSS31 cells inhibited HGF-induced activation of Src as well as capillary morphogenesis. The HGF-induced capillary morphogenesis of human umbilical vein endothelial cells was also inhibited by PP2 and was reduced by the downregulation of Src by small interfering RNA. These results suggest that HGF induces capillary morphogenesis of endothelial cells through Src. | |||||
書誌情報 |
Biochemical and biophysical research communications 巻 344, 号 2, p. 617-622, 発行日 2006-06-02 |
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出版者 | ||||||
出版者 | Elsevier Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0006291X | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1090-2104 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00564395 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 16620780 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.bbrc.2006.03.183 | |||||
権利 | ||||||
権利情報 | Copyright c 2006 Elsevier Inc. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Biochemical and biophysical research communications, 344(2), pp.617-622; 2006 |