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In vitro activity of garenoxacin against Streptococcus pneumoniae mutants with characterized resistance mechanisms.
http://hdl.handle.net/10069/22297
http://hdl.handle.net/10069/2229760fcc1b1-8d5a-42f2-8f38-d9038acb6ca6
名前 / ファイル | ライセンス | アクション |
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AAC53_3572.pdf (152.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-10-28 | |||||
タイトル | ||||||
タイトル | In vitro activity of garenoxacin against Streptococcus pneumoniae mutants with characterized resistance mechanisms. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yamamoto, Kazuko
× Yamamoto, Kazuko× Yanagihara, Katsunori× Sugahara, Kazuyuki× Imamura, Yoshifumi× Seki, Masafumi× Izumikawa, Koichi× Kakeya, Hiroshi× Yamamoto, Yoshihiro× Hirakata, Yoichi× Kamihira, Shimeru× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We evaluated the potency of garenoxacin in selecting resistant Streptococcus pneumoniae mutants by determining its mutant prevention concentration, using strains with and without topoisomerase gene mutations, and compared its potency to that of other quinolones. Garenoxacin had a significantly greater potency against pneumococci, including strains containing topoisomerase mutations. Genetic analysis of the S. pneumoniae mutants created by garenoxacin revealed that the gyrA gene was a primary target of garenoxacin. | |||||
書誌情報 |
Antimicrobial agents and chemotherapy 巻 53, 号 8, p. 3572-3575, 発行日 2009-08 |
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出版者 | ||||||
出版者 | American Society for Microbiology | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00664804 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1098-6596 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00542574 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 19451290 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1128/AAC.00176-09 | |||||
権利 | ||||||
権利情報 | Copyright c 2009, American Society for Microbiology. All Rights Reserved. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Antimicrobial agents and chemotherapy, 53(8), pp.3572-3575; 2009 |